Regular ArticleMammalian Sperm Contain a Ca2+-Sensitive Phospholipase C Activity That Can Generate InsP3 from PIP2 Associated with Intracellular Organelles☆
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Keywords
sperm
sperm factor
phospholipase C
egg
fertilization
calcium
inositol 1,4,5-trisphosphate
phosphatidylinositol 4,5-bisphosphate
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Abbreviations used: EGTA, ethylene glycol bis(β-aminoethylether)-N,N,N-tetraacetic acid; InsP3, inositol 1,4,5-trisphosphate; PIP2, phosphatidylinositol 4,5-bisphosphate; PLC, phosphoinositide-specific phospholipase C; PBS, phosphate-buffered saline.
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