Regular ArticleMechanical Stretch Induces Activation of Skeletal Muscle Satellite Cells in Vitro
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2022, Biochemistry and Biophysics ReportsCitation Excerpt :HGF [31,32], also known as scatter factor, is a pleiotropic multidomain-protein in the plasminogen subfamily. The active form of HGF is a heterodimer of α- and β-chains previously demonstrated to activate quiescent satellite cells to enter the cell cycle in postnatal muscle growth and regeneration through its release from extracellular tethering and presentation to the cell-membrane receptor c-met [23,24,33–35]. HGF α-chain (about 60 kDa) is composed of a N-terminal domain (also called the PAN/APPLE-like domain) followed by four Kringle domains (K1 to K4), and originally linked to a 30-kDa β-chain subunit (Fig. S1 panel A).
Skeletal muscle
2022, Sturkie's Avian Physiology
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