Regular ArticlecDNA Cloning and Mapping of a Novel Islet-Brain/JNK-Interacting Protein
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2015, Journal of Biomedical InformaticsCitation Excerpt :MAFA, implicated in animal models of type 2 diabetes, is markedly decreased in humans with type 2 diabetes [29]. MAPK8IP2, the IB2 gene, is a novel candidate gene for diabetes [30]. SOCS2, which is ubiquitously expressed in human tissues, has been found to contribute to susceptibility to type 2 diabetes in a Japanese population [31].
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2011, European Journal of Cell BiologyDisassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis
2011, Experimental Cell ResearchCitation Excerpt :A family of scaffold proteins, called JNK-Interacting Proteins (JIPs), has been identified [31–34]. These include JIP1 and JIP2 [also known as IB1/2 [35,36]] and JIP3/JSAP [33,37]. These proteins are thought to organise the components of the JNK pathway into specific signalling complexes [38].
Mammalian MAP Kinases
2009, Handbook of Cell Signaling, Second EditionG-Protein-Coupled Receptors, Signal Fidelity, and Cell Transformation
2009, Handbook of Cell Signaling, Second Edition
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