Journal of Molecular Biology
Volume 251, Issue 4, 25 August 1995, Pages 563-573
The Three-dimensional Crystal Structure of Cholera Toxin☆,☆☆,★
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Keywords
crystal structure
cholera toxin
choleragenoid
enterotoxins
ADP-ribosylation
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Abbreviations used: CT, cholera toxin (choleragen); CTB, B subunit pentamer of cholera toxin (choleragenoid); LT, heat-labile enterotoxin fromEscherichia coli; ST, shiga toxin; PT, pertussis toxin; VT, verotoxin; GM1Galβ1-3GalNAcβ1-(NeuAcα2-3)4Galβ1-4Glcβ1 ceramide; r.m.s., root-mean-square.
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Present address: D. L. Scott, Medical Services, Massachusetts General Hospital, Boston, MA 02114, USA.
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Present address: B. D. Spangler, Department of Biological Sciences and Department of Chemistry, Northern Illinois University, Dekalb, IL 60115, USA.
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