Early Evolution of Cytochrome bc Complexes

doi:10.1006/jmbi.2000.3915

Journal of Molecular Biology

Volume 300, Issue 4, 21 July 2000, Pages 663-675

https://doi.org/10.1006/jmbi.2000.3915 Get rights and content

Abstract

Primary structures, functional characteristics and phylogenetic relationships of subunits of cytochrome bc complexes from phylogenetically diverse bacterial and archaeal species were analysed. A single case of lateral gene transfer, i.e. the import of an ϵ-proteobacterial cytochrome bc₁ complex into Aquificales, was identified. For the enzyme in the remainder of the species studied, the obtained phylogenies were globally in line with small subunit rRNA trees. The distribution of a few key phylogenetic markers, such as contiguousness of cytochrome b, nature of the c-type subunit or spacing between b-heme ligands, are discussed. A localised modification of previous tree topologies is proposed on the basis of the obtained data. The comparison of extant enzymes furthermore allowed us to define the minimal functional and evolutionary core of the enzyme. The data furthermore suggest that the ancestral enzyme was put together from subunits that previously had played a role in other electron transfer chains.

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^☆: Abbreviations used: SSU, small subunit; ORF, open reading frame; ISP, iron-sulphur protein; SUIV, subunit IV; cyt, cytochrome; UQ, ubiquinone; MK, menaquinone; PQ, plastoquinone; CQ, caldariellaquinone; RC, photosynthetic reaction centre

^☆☆: Edited by G. Von Heijne

^f1: These authors contributed equally to this work.

^f2: Corresponding author

^f3: E-mail address of the corresponding author: [email protected]

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Journal of Molecular Biology

Review ArticleEarly Evolution of Cytochrome bc Complexes☆,☆☆

Abstract

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Structure

Biochim. Biophys. Acta

FEBS Letters

Biochem. Biophys. Res. Commun.

Advan. Inorg. Chem.

J. Biol. Chem.

Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori

Nature

Diversity of cytochrome bc complexes: example of the Rieske protein in green sulfur bacteria

J. Bacteriol.

Structure of the soluble domain of cytochrome f from the cyanobacterium Phormidium laminosum

Biochemistry

Respiratory chains in the last common ancestor of living organisms

J. Mol. Evol.

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EMBO J.

Distribution of isoprenoid quinone structural types in bacteria and their taxonomic implications

Microbiol. Rev.

The complete genome of the hyperthermophilic bacterium Aquifexaeolicus

Nature

Evolution and origins of the bc1 and b6 f complexes

Cloning and sequence analysis of the structural gene for the bc1-type Rieske iron-sulfur protein from Thermus thermophilus HB8

J. Bioenerg. Biomembr.

Mutational studies of the cytochrome bc1 complexes

Review Article
Early Evolution of Cytochrome bc Complexes☆,☆☆

Evolution and origins of the bc₁ and b₆ f complexes

Cloning and sequence analysis of the structural gene for the bc₁-type Rieske iron-sulfur protein from Thermus thermophilus HB8

Mutational studies of the cytochrome bc₁ complexes