Journal of Molecular Biology
Regular ArticleMacromolecular Assemblage of Aminoacyl-tRNA Synthetases: Quantitative Analysis of Protein-Protein Interactions and Mechanism of Complex Assembly☆,☆☆
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2019, Journal of Biological ChemistryCitation Excerpt :The source of viral LysRS has been an active area of investigation. In higher eukaryotic cells, LysRS has been reported to be found in the nucleus (63), in mitochondria (64), assembled in the MSC in the cytosol (65), and associated with the plasma membrane (66, 67). Early studies suggested that newly synthesized LysRS is packaged into the virus prior to assembly into the MSC (66, 68).
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Abbreviations used: aminoacyl-tRNA synthetases are abbreviated by the three-letter code of the amino acid followed by RS (for instance, LysRS stands for lysyl-tRNA synthetase); Ni-NTA, nickel nitrilotriacetic acid; BSA, bovine serum albumin; SPR, surface plasmon resonance
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Edited by J. Karn
- f1
Corresponding author
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E-mail address of the corresponding author: [email protected]