Regular ArticleOxygen sensors and angiogenesis
References (66)
Hypoxia-inducible factor 1: oxygen homeostasis and diseases pathophysiology
Trends Mol Med
(2001)- et al.
Identification of the renal erythropoietin-producing cells using transgenic mice
Kidney Int
(1993) - et al.
Activation of hypoxia-inducible transcription factor depends primarily on redox-sensitive stabilization of its a subunit
J Biol Chem
(1996) - et al.
Hypoxia-inducible factor 1 α(HIF-1 α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions
J Biol Chem
(1997) Induction of endothelial PAS domain protein-1 by hypoxia: characterization and comparison with hypoxia-inducible factor-1a
Blood
(1998)- et al.
Activation of hypoxia inducible factor-1; definition of regulatory domains within the a subunit
J Biol Chem
(1997) - et al.
Transactivation and inhibitory domains of hypoxia-inducible factor 1a. Modulation of transcriptional activity by oxygen tension
J Biol Chem
(1997) - et al.
Oxygen-regulated and transactivating domains in endothelial PAS protein 1: comparison with hypoxia inducible factor-1α
J Biol Chem
(1999) - et al.
Hypoxia inducible factor-a binding and ubiquitylation by the von Hippel–Lindau tumor suppressor protein
J Biol Chem
(2000) - et al.
Selection of mutant CHO cells with constitutive activation of the HIF system and inactivation of the von Hippel–Lindau tumor suppressor
J Biol Chem
(2001)
The VHL tumour-suppressor gene paradigm
Trends Genet
(1998)
Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2 α
Am J Pathol
(1998)
The von Hippel–Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix
Mol Cell
(1998)
Desferrioxamine induces erythropoietin gene expression and hypoxia-inducible factor 1 DNA-binding activity: implications for models of hypoxia signal transduction
Blood
(1993)
The lore of the RINGs: substrate recognition and catalysis by ubiquitin ligases
Trends Cell Biol
(2000)
Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes
Curr Opin Struct Biol
(1999)
The von Hippel–Lindau protein interacts with hnRNP A2 and regulates its expression
J Biol Chem
(2001)
Expression and characterization of hypoxia-inducible factor (hif)-3alpha in human kidney: suppression of hif-mediated gene expression by hif-3alpha
Biochem Biophys Res Commun
(2001)
Activation of the HIF pathway in cancer
Curr Opin Genet Dev
(2001)
Effect of oxygen on developing retinal vessels with particular reference to the problem of retrolental fibroplasia
Br J Ophthalmol
(1954)
Oxygen tension regulates the expression of angiogenesis factor by macrophages
Science
(1983)
Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis
Nature
(1992)
Oxygen sensing and molecular adaptation to hypoxia
Physiol Rev
(1996)
The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia
Proc Natl Acad Sci USA
(2001)
C. elegans EGL-9 and mammalian homologues define a family of dioxygenases that regulate HIF by prolyl hydroxylation
Cell
(2001)
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2tension
Proc Natl Acad Sci USA
(1995)
Regulation of hypoxia-inducible factor 1a is mediated by an oxygen-dependent domain via the ubiquitin-proteasome pathway
Proc Natl Acad Sci USA
(1998)
Induction of HIF-1 alpha in response to hypoxia is instantaneous
FASEB J
(2001)
An essential role for p300/CBP in the cellular response to hypoxia
Proc Natl Acad Sci USA
(1996)
Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha
Mol Cell Biol
(2000)
Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1a
EMBO J
(1998)
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
Nature
(1999)
Cited by (0)
- 1
Corresponding author. [email protected]
Copyright © 2002 Elsevier Science Ltd. All rights reserved.