Regular ArticleThe Importance of Fiber Biopersistence and Lung Dose in Determining the Chronic Inhalation Effects of X607, RCF1, and Chrysotile Asbestos in Rats
References (42)
- et al.
Evalution of the oncogenic potential of man-made vitreous fibers: the inhalation model
Annals of Occupational Hygiene
(1995) - et al.
Chronic inhalation toxicity of size-separated glass fibers in Fischer 344 rats
Fundam. Appl. Toxicol.
(1993) - et al.
Biopersistence of man-made vitreous fibers and crocidolite asbestos in the rat lung following inhalation
Fundam. Appl. Toxicol.
(1996) - et al.
Use of lung toxicity and lung particle clearance to estimate the maximum tolerated dose (MTD) for a fiber glass chronic inhalation study in the rat
Fundam. Appl. Toxicol.
(1996) Deposition and retention of fibers in the human lung
- Bauer, J. F. Law, B. D. Roberts, K. A. Solubility and durability of manmade mineral fibers in physiological fluids,...
- et al.
Evaluation of soluble fibers using the inhalation biopersistence model, a nine-fiber comparison
Inhal. Tox.
(1996) Studies by National Institute of Environmental Health Sciences. Bureau of Mines Report No. 8452
(1980)- et al.
The flow-past chamber: An improved nose-only exposer system for rodents
Am. Ind. Hyg. Assoc. J.
(1983) Chemical Anatomy, Physiology, and Pathology of Extracellular Fluid
(1967)
The effects of fibrous glass dust on the lungs of animals. In US Department of Health Education and Welfare. Occupational exposure to fibrous glass: Proceedings of a symposium, College Park, Maryland, Washington, DC
Tumor incidence in Fischer 344 rats: NTP historical data
Chronic inhalation study of fiber glass and amosite asbestos in hamsters: Twelve-month preliminary results
Environ. Health Perspec.
Biopersistence of synthetic vitreous fibers and amosite asbestos in the rat lung following inhalation
Toxicol. Appl. Pharmacol.
Physical and chemical transformation of synthetic vitreous fibres in the lung and in vitro
J. Occup. Health Safety–Aust, NZ
Follow up study of workers exposed to man made mineral fibres
Br. J. Ind. Med.
Solubility of polymeric organic fibers and man-made vitreous fibers in gambles solution
Inhalation Toxicology
Cited by (74)
A case study of the translocation, bioprocessing and tissue interactions of EMP following inhalation exposure
2018, Toxicology and Applied PharmacologyRefractory ceramic fibers: Fiber characteristics, potential health effects and clinical observations
2018, Toxicology and Applied PharmacologyCitation Excerpt :AES wool fiber diameters are similar to those for RCF and, in consequence, airborne fiber concentrations (also measured as part of the industry PSP) for comparable FJCs are also quite similar. Biopersistence and other studies (see e.g., Brown et al., 2002; Brown and Harrison, 2012; Campopiano et al., 2014; Cavallo et al., 2015; Harrison and Brown, 2011; Hesterberg et al., 1998b; Maxim et al., 1999; Ohsawa, 2005; Ziemann et al., 2014) have shown AES wool fibers to have significantly lower biopersistence than RCFs and minimal toxicology in subchronic studies. Hesterberg et al., 1998b performed a chronic (2 year) nose-only inhalation study that indicated that one AES wool (×607) was neither fibrogenic nor carcinogenic.
Insulation fiber deposition in the airways of men and rats. A review of experimental and computational studies
2018, Regulatory Toxicology and Pharmacology
W. J. CampbellC. W. HigginsA. G. Wylie
- 1
To whom reprint request should be addressed.