Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
An, W.G., M. Kanckal, M.C. Simon, E. Multepe, M.V. Blagosklonny, and L.M. Neckers. 1998. Stabilization of wild-type p53 by hypoxia-inducible factor lalpha. Nature 392: 405–405
Bunn, H.F. and R.O. Poyton. 1996. Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev 76: 839–885.
Choi, K., M. Kennedy, A. Kazarov, J.C. Papadimitriou, and G. Keller. 1998. A common precursor for hematopoietic and endothelial cells. Development 125: 725–732.
Ferrara, N., K. Carver-Moore, H. Chen, M. Dowd, L. Lu, K.S. O’Shea, L. Powell-Braxton, K.J. Hillan, and M.W. Moore. 1996. Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene. Nature 380: 439–442.
Fischer, B. and B.D. Bavister. 1993. Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits. J Reprod Fertil 99: 673–679.
Gassmann, M., J. Fandrey, S. Bichet, M. Wartenberg, H.H. Marti, C. Bauer, R.H. Wenger, and H. Acker. 1996. Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells. Proc Natl Acad Sci USA 93: 2867–2872.
Genbacev, O., Y. Zhou, J.W. Ludlow, and S.J. Fisher. 1997. Regulation of human placental development by oxygen tension. Science 277: 1669–1672.
Katoh, O., T. Takahashi, T. Oguri, K. Kuramoto, K. Mihara, M. Kobayashi, S. Hirata, and H. Watanabe. 1998. Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor. Cancer Res 58: 5565–5569.
Keller, G., M. Kennedy, T. Papayannopoulou, and M.V. Wiles. 1993. Hematopoietic commitment during embryonic stem cell differentiation in culture. Mol Cell Biol 13: 473–486.
Kennedy, M., M. Firpo, K. Choi, C. Wall, S. Robertson, N. Kabrun, and G. Keller. 1997. A common precursor for primitive erythropoiesis and definitive haematopoiesis. Nature 386: 488–493.
Kozak, K.R., B. Abbott, and O. Hankmson. 1997. ARNT-deficient mice and placental differentiation. Dev Biol 191: 297–305.
Lin, C.S., S.K. Lim, V. D’Agati, and F. Costantini. 1996. Differential effects of an erythropoietin receptor gene disruption on primitive and definitive erythropoiesis. Genes Dev 10: 154–164.
Maltepe, E., J.V. Schmidt, D. Baunoch, C.A. Bradfield, and M.C. Simon. 1997. Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT. Nature 386: 403–407.
Medvinsky, A. and E. Dzierzak. 1996. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 86: 897–906.
Mortensen, R.M., D.A. Conner, S. Chao, A.A. Geisterfer-Lowrance, and J.G. Seidman. 1992. Production of homozygous mutant ES cells with a single targeting construct. Mol Cell Biol 12: 2391–2395.
Olson, M.C., E.W. Scott, A.A. Hack, G.H. Su, D.G. Tenen, H. Singh, and M.C. Simon. 1995. PU. 1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation. Immunity 3: 703–714.
Phillips, P.G., L.M. Birnby, and A. Narendran. 1995. Hypoxia induces capillary network formation in cultured bovine pulmonary microvessel endothelial cells. Am J Physiol 268: L789–800.
Robb, L., N.J. Elwood, A.G. Elefanty, F. Kontgen, R. Li, L.D. Barnett, and C.G. Begley. 1996. The scl gene product is required for the generation of all hematopoietic lineages in the adult mouse. Embo J 15: 4123–4129.
Rodesch, P., P. Simon, C. Donner, and E. Jauniaux. 1992. Oxygen measurements in endometrial and trophoblastic tissues during early pregnancy. Obstet Gynecol 80: 283–285.
Shalaby, F., J. Ho, W.L. Stanford, K..D. Fischer, A.C. Schuh, L. Schwartz, A. Bernstein, and J. Rossant. 1997. A requirement for Flkl in primitive and definitive hematopoiesis and vasculogenesis. Cell 89: 981–990.
Shweiki, D., A. Itin, D. Soffer, and E. Keshet. 1992. Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis. Nature 359: 843–845.
Wang, G.L., B.H. Jiang, E.A. Rue, and G.L. Semenza. 1995. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension. Proc Natl Acad Sci USA 92: 5510–5514.
Wang, L.C., W. Swat, Y. Fujiwara, E. Davidson, J. Visvader, F. Kuo, F.W. Alt, D.G. Gilhland, T.R. Golub, and S.H. Orkin. 1998. The TEE/ETV6 gene is required specifically for hematopoiesis in the bone marrow. Genes Dev 12: 2392–2402.
Wenger, R.H. and M. Gassmann. 1997. Oxygen(es) and the hypoxia-inducible factor-1. Biol Chem 378: 609–616.
Wood, S.M., J.M. Gleadle, C.W. Pugh, O. Hankinson, and P.J. Ratcliffe. 1996. The role of the aryl hydrocarbon receptor nuclear translocator (ARNT) in hypoxic induction of gene expression. Studies in ARNT-deficient cells. J Biol Chem 271: 15117–15123.
Wti, H., X. Li u, R. Jaenisch, and H.F. Lodish. 1995. Generation of committed erythroid BFUE and CFU-E progenitors docs not require erythropoietin or the erythropoietin receptor. Cell 83: 59–67.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Kluwer Academic Publishers
About this chapter
Cite this chapter
Adelman, D.M., Maltepe, E., Simon, M.C. (2002). HIF-1 is Essential for Multilineage Hematopoiesis in the Embryo. In: Lahiri, S., Prabhakar, N.R., Forster, R.E. (eds) Oxygen Sensing. Advances in Experimental Medicine and Biology, vol 475. Springer, Boston, MA. https://doi.org/10.1007/0-306-46825-5_26
Download citation
DOI: https://doi.org/10.1007/0-306-46825-5_26
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-306-46367-9
Online ISBN: 978-0-306-46825-4
eBook Packages: Springer Book Archive