Abstract
The availability of an increasing number of vertebrate genomes has enabled comparative methods to infer functional sequences based on evolutionary constraint. Although this has proved powerful for gene identification, significant progress has also been made in uncovering gene regulatory sequences such as distant acting transcriptional enhancers. These pursuits have led to the development of a variety of valuable databases and resources that should serve as a routine toolbox for biological discovery.
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Cheng, JF., Priest, J.R., Pennacchio, L.A. (2007). Comparative Genomics. In: Zhang, J., Rokosh, G. (eds) Cardiac Gene Expression. Methods in Molecular Biology, vol 366. Humana Press. https://doi.org/10.1007/978-1-59745-030-0_13
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DOI: https://doi.org/10.1007/978-1-59745-030-0_13
Publisher Name: Humana Press
Print ISBN: 978-1-58829-352-7
Online ISBN: 978-1-59745-030-0
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