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TOR pp 73–84Cite as

Autophagy in Yeast: ATOR-Mediated Response to Nutrient Starvation

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 279))

Abstract

TOR plays a key role in cell growth and cell-cycle progression, but in addition recent studies have shown that TOR is also involved in the regulation of a number of molecular processes associated with nutrient deprivation, such as autophagy. In budding yeast, TOR negatively regulates activation of Apg1 protein kinase, which is essential for the induction of autophagy. This review describes recent research in this field and the mechanism by which TOR mediates induction of autophagy.

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Author information

Authors and Affiliations

  1. Department of Cell Biology, National Institute for Basic Biology, 444-8585, Okazaki, Japan

    Y. Kamada, T. Sekito & Y. Ohsumi

Authors
  1. Y. Kamada
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  2. T. Sekito
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  3. Y. Ohsumi
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Editor information

Editors and Affiliations

  1. Friedrich-Miescher-Institute, Maulbeerstrasse 66, 4058, Basel, Switzerland

    George Thomas

  2. Whitehead Institute, 9 Cambridge Center, Cambridge, MA, 02142, USA

    David M. Sabatini MD, PhD

  3. Biozentrum, University of Basel, Klingelbergstrasse 70, 4056, Basel, Switzerland

    Michael N. Hall

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© 2004 Springer-Verlag Berlin Heidelberg

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Kamada, Y., Sekito, T., Ohsumi, Y. (2004). Autophagy in Yeast: ATOR-Mediated Response to Nutrient Starvation. In: Thomas, G., Sabatini, D.M., Hall, M.N. (eds) TOR. Current Topics in Microbiology and Immunology, vol 279. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18930-2_5

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  • DOI: https://doi.org/10.1007/978-3-642-18930-2_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62360-8

  • Online ISBN: 978-3-642-18930-2

  • eBook Packages: Springer Book Archive

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