References
Ahouse, J. J., Hagerman, C. L., Mittal, P., Gilbert, D. J., Copeland, N. G., Jenkins, N. A., and Simister, N. E. Mouse MHC class I0like Fc receptor encoded outside the MHC. J Immunol 151: 6076–6088, 1993
Anderson, L. and Davies, C. J. The major histocompatibility complex. In B. M. Goddeeris and W. I. Morrison (eds.): Cell-mediated Immunity in Ruminants, CRC press, in press
Bahram, S., Bresnahan, M., Geraghty, D. E., and Spies, T. A second lineage of mammalian major histocompatibility complex class I genes. Proc Natl Acad Sci USA 91: 6259–6263, 1994
Bartl, S. and Weissman, I. L. Isolation and characterization of major histocompatibility complex class II B genes from the nurse shark. Proc Natl Acad Sci USA 91, in press
Beck, S., Alderton, R., Kelly, A., Khurshid, F., Radley, E., and Trowsdale, J. DNA sequence analysis of 66 kb of the human MHC class II region encoding a cluster of genes for antigen processing. J Mol Biol 228: 433–441, 1992
Beck, S., Hanson, I., Kelly, A., Pappin, D. J. C., and Trowsdale, J. A homologue of the Drosophila female sterile homeotic (fsh) gene in the class II region of the human MHC. DNA Sequence 2: 203–210, 1992
Belich, M. P., Glynne, R. J., Senger, G., Sheer, D., and Trowsdale, J. Proteasome components with reciprocal expression to that of the MHC-encoded LMP proteins. Curr Biol 4: 769–776, 1994
Betz, U. A. K., Mayer, W. E., and Klein, J. Major histocompatibility complex class I genes of the coelacanth Latimeria chalumnae. Proc Natl Acad Sci USA 91, in press
Bernardi, G. The isochore organisation of the human genome. Annu Rev Genet 23: 637–661, 1986
Bernardi, G. and Bernardi, G. Compositional constraints and genome evolution. J Mol Evol 24: 1–11, 1986
Bird, A. P. CpG islands as gene markers in the vertebrate nucleus. Trends Genet 3: 342–347, 1987
Brenner, S., Elgar, G., Sandford, R., Macrae, A., Venkatesh, B., and Aparicio, S. Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome. Nature 366: 265–268, 1993
Briles, W. E., Goto, R. M., Auffray, C., and Miller, M. M. A polymorphic system related to but genetically independent of the chicken major histocompatibility complex. Immunogenetics 37: 408–414, 1993
Calabi, F. and Milstein, C. A novel family of human major histocompatibility-related genes not mapping to chromosome 6. Nature 323: 540–543, 1986
Campbell, R. D. The molecular genetics of components of the complement system. Baillieres Clin Rheumatol 2 (sn3): 547–575, 1988
Campbell, R. D., Law, S. K., Reid, K. B., and Sim, R. B. Structure, organization, and regulation of the complement genes. Annu Rev Immunol 6: 161–195, 1988
Campbell, R. D. and Trowsdale, J. Map of the human MHC. Immunol Today 14: 349–352, 1993
Carrington, M., Colonna, M., Spies, T., Stephens, J. C., and Mann, D. L. Haplotypic variation of the transporter associated with antigen processing (TAP) genes and their extension of HLA class II region haplotypes. Immunogenetics 37: 266–273, 1993
Carter, C. A., Murphy, G., and Fabre, J. W. A polymorphic HLA-DPA-like locus, unlinked to the rat major histocompatibility complex. Immunogenetics 34: 277–280, 1991
Carter, C. A., Murphy, G., Fabre, J. W., and Lund, T. Physical mapping of the rat MHC class II genes shows a high level of interspecies conservation. Genomics 22: 451–455, 1994
Ceman, S., Rudersdorf, R., Long, E. O., and Demars, R. MHC class II deletion mutant expresses normal levels of transgene encoded class II molecules that have abnormal conformation and impaired antigen presentation ability. J Immunol 149: 754–761, 1992
Cho, S., Attaya, M., Brown, M. G., and Monaco, J. J. A cluster of transcribed sequences between the Pb and Ob genes of the murine major histocompatibility complex. Proc Natl Acad Sci USA 88: 5197–5201, 1991
Cho, S., Attaya, M., and Monaco, J. J. New class II-like genes in the murine MHC. Nature 353: 573–576, 1991
Chouchane, L. and Kindt, T. J. Mapping of the rabbit MHC reveals that class I genes are adjacent to the DR subregion and defines an insertion/deletion-related polymorphism in the class II region. J Immunol 149: 1216–1222, 1992
Ciccione, E., Colonna, M., Viale, O., Pende, D., Di Donato, C., Reinharz, D., Amoroso, A., Jeannet, M., Guardiola, J., Moretta, A., Spies, T., Strominger, J., and Moretta, L. Susceptibility or resistance to lysis by alloreactive natural killer cells is governed by a gene in the human major histocompatibility complex between Bf and HLA-B. Proc Natl Acad Sci USA 87: 9794–9797, 1990
Colonna, M., Bresnahan, M., Bahram, S., Strominger, J. L., and Spies, T. Allelic variants of the human putative peptide transporter involved in antigen processing. Proc Natl Acad Sci USA 89: 3932–3936, 1992
Craig, J. M. and Bickmore, W. A. Chromosome bands-flavours to savour. Bioassays 15: 349–354, 1993
Davies, J. L., Kawaguchi, Y., Bennett, S. T., Copeman, J. B., Cordell, H. J., Pritchard, L. E., Reed, P. W., Gough, S. C. L., Jenkinds, S. C., Palmer, S. M., Balfour, K. M., Rowe, B. R., Farral,, M., Barnett, A. H., Bain, S. C., and Todd, J. A. A genome-wide search for human type 1 diabetes susceptibility genes. Nature 371: 130–136, 1994
Dawkins, R. L., Christiansen, F. T., Kay, P. H., Garlepp, M. J., McCluskey, J., Hollingsworth, P. N., and Zilko, P. J. Disease associations with complotypes, supratypes and haplotypes. Immunol R Rev 70: 5–22, 1983
Degli-Esposti, M. A., Abraham, L. J., McCann, V., Spies, T., Christiansen, F. T., and Dawkins, R. L. Ancestral haplotypes reveal the role of the central MHC in the immunogenetics of IDDM. Immunogenetics 36: 345–356, 1992
Degli-Esposti, M. A., Andreas, A., Christiansen, F. T., Schalke, B., Albert, E., and Dawkins, R. L. An approach to the localization of the susceptibility genes for generalized myasthenia gravis by mapping recombinant ancestral haplotypes. Immunogenetics 35: 355–364, 1992
Delarbre, C., Jaulin, C., Kourilsky, P., and Gachelin, G. Evolution of the major histocompatibility complex: a hundred-fold amplification of the MHC class I genes in the African pigmy mouse Nannomys setulosus. Immunogenetics 37: 29–38, 1992
Diamond, J. The Rise and Fall of the Third Chimpanzee, Vintage, London, 1990
Dixon, B., Stet, R. J. M., van Erp, S. H. M., and Pohajdak, B. Characterization of β2-microglobulin transcripts from two teleost species. Immunogenetics 38: 27–34, 1993
Dominguez-Steglich, M., Auffray, M. C., and Schmid, M. Linkage of the chicken MHC to the nucleolus organizer region visualized using non-isotopic in situ hybridization. J Heredity 82: 503–505, 1991
Dunham, I., Sargent, C. A., Kendall, E., and Campbell, R. D. Characterization of the class III region in different MHC haplotypes by pulsed-field gel electrophoresis. Immunogenetics 32: 175–182, 1990
El Kahloun, A., Vernet, C., Jouanolle, A. M., Boretto, J., Mauvicux, V., Le Gall, J. Y., David, V., and Pontarotti, P. A. A continuous restriction map from HLA-E to HLA-F. Structural comparison between different HLA-A haplotypes. Immunogenetics 35: 183–189, 1992
Ellengren, H., Hartman, G., Johansson, M., and Andersson, L. Major histocompatibility complex monomorphism and low levels of DNA fingerprinting variability in a reintroduced and rapidly expanding population of beavers. Proc Natl Acad Sci USA 90: 8150–5153, 1993
Finnegan, D. J. Transposable elements. Curr Opin Gen Dev 2: 861–867, 1992
Flajnik, M. F., Kasahara, M., Shum, B. P., Salter-Cid, L., Taylor, E., and DuPasquier, L. A novel type of class I gene organization in vertebrates: a large family of non-MHC-linked class I genes is expressed at the RNA level in the amphibian Xenopus. EMBO 12: 4385–4396, 1993
Fling, S. P., Arp, B., and Pious, D. HLA-DMA and —DMB genes are both required for MHC class II/peptide complex formation in antigen-presenting cells. Nature 368: 554–558, 1994
Freije, J. P., Fueyo, A., Uría, J., and López-Otín, C. Human Zn-α2-glycoprotein cDNA cloning and expression analysis in benign and malignant breast tissues. FEBS Lett 290: 247–249, 1991
Freije, J. P., Fueyo, A., Uría, J. A., Velasco, G., Sánchez, L. M., Lopez-Boado, Y. S., and López-Otín, C. Human Zn-α2-glycoprotein: complete genomic sequence, identification of a related pseudogene and relationship to class I major histocompatibility complex genes. Genomics 18: 575–587, 1993
Gasser, D. L., Sternberg, N. L., Pierce, J. C., Goldner-Sauve, A., Feng, H., Haq, A. K., Spies, T., Hunt, C., Buetow, K. H., and Chaplin, D. D. P1 and cosmid clones define the organization of 280 kb of the mouse H-2 complex containing the Cps-1 and Hsp70 loci. Immunogenetics 39: 48–55, 1994
Geraghty, D. E. Structure of the HLA class region and expression of its resident genes. Curr Opin Immunol 5: 3–7, 1993
Gill, T. Current status of the major histocompatibility complex in the rat. Transplantation proceedings, in press
Grahovac, B., Schonbach, C., Brandle, U., Mayer, W. E., Golubic, M., Figueroa, F., Trowsdale, J., and Klein, J. Conservative evolution of the MHC-DP region in anthropoid primates. Hum Immunol 37: 75–84, 1992
Grimholt, U., Hordvik, I., Fosse, V. M., Olsaker, I., Endresen, C., and Lie, Ø.Molecular cloning of major histocompatibility complex class I cDNAs from Atlantic salmon (Salmo salar). Immunogenetics 37: 469–473, 1993
Guillemot, F., Billault, A., and Auffray, C. Physical linkage of a guanine nucleotide-binding protein-related gene to the chicken major histocompatibility complex. Proc Natl Acad Sci USA 86: 4594–4598, 1989
Guillemot, F., Billault, A., Pourquie, O., Behar, G., Chausse, A. M., Kreibich, G., and Auffray, C. A molecular map of the chicken major histocompatibility complex: the class II beta genes are closely linked to the class I genes and the nucleolar organizer. EMBO 7: 2775–2785, 1988
Guillemot, F., Kaufman, J. F., Skjoedt, K., and Auffray, C. The major histocompatibility complex in the chicken. TIGS 5: 300–304, 1989
Gustafsson, K. and Anderson, L. Structure and polymorphism of horse MHC class II DRB genes: convergent evolution in the antigen binding site. Immunogenetics 39: 355–358, 1994
Haas, D. A., Boss, J. M., Strominger, J. L., and Spies, T. A highly diverged beta 1 exon in the DR region of the human MHC: sequence and evolutionary implications. Immunogenetics 25: 15–20, 1987
Haas, W., Pereira, P., and Tonegawa, S. Gamma/delta T cells. Annu Rev Immunol 11: 637–685, 1993
Hanson, I. M. and Trowsdale, J. Colinearity of novel genes in the class II regions of the MHC in mouse and human. Immunogenetics 34: 5–11, 1991
Hardy, D. A., Bell, J. L., Long, E. O., Lindsten, T., and McDevitt, H. O. Mapping of the class II region of the human major histocompatibility complex by pulsed-field gel electrophoresis. Nature 323: 453–455, 1986
Hashimoto, K., Nakanashi, K. T., and Kurosawa, Y. Isolation of carp genes encoding major histocompatibility complex antigens. Proc Natl Acad Sci USA 87: 6863–6867, 1992
Hashimoto, K., Nakanishi, T., and Kurosawa, Y. Identification of a shark sequence resembling the major histocompatibility complex class I alpha 3 domain. Proc Natl Acad Sci USA 89: 2209–2212, 1992
Hordvik, I., Grimholt, U., Fosse, V. M., Lie, Ø., and Endresen, C. Cloning and sequence analysis of cDNs encoding the MHC class II β chain in Atlantic salmon (Salmon salar). Immunogenetics 37: 437–441, 1993
Howard, J. C. Restrictions on the use of antigenic peptides by the immune system. Proc Natl Acad Sci USA 90: 3777–3779, 1993
Humpreys, T. and Reinherz, E. L. Invertebrate immune recognition, natural immunity and the evolution of positive selection. Immunol Today 15: 316–320, 1994
Ikemura, T. and Aota, S. I. Global variation in G + C content along vertebrate genome DNA: possible correlation with chromosome band structures. J Mol Biol 203: 1–13, 1988
Ikemura, T., Matsumoto, K., Ishihara, N., Ando, A., and Inoko, H. Giant G + C% mosaic structures in the HLA locus and a border between the mosaic domains. In K. Tsuji, M. Aizawa, and T. Sasazuki (eds.): HLA 1991, pp. 125–128, Oxford University Press, Oxford, 1992
Ikemura, T., Wada, K. N., and Aota, S. I. Giant G + C% mosaic structures of the human genome found by arrangement of genbank human DNA sequences according to genetic positions. Genomics 8: 207–216, 1990
Joly, E., Deverson, E. V., Coadwell, J. W., Gunther, E., Howard, J. C., and Butcher, G. W. The distribution of Tap2 alleles among laboratory rat RT1 haplotypes. Immunogenetics 40: 45–53, 1994
Jurka, J., Walichiewicz, J., and Milosavljevic, A. Prototypic sequences for human repetitive DNA. J Mol Evol 35: 286–291, 1992
Juul-Madsen, H. R., Glamann, J., Madsen, H. O., and Simonsen, M. MHC class II beta-chain expression in the rainbow trout. Scand J Immunol 35: 687–694, 1992
Kahloun, A. E., Vernet, C., Jouanolle, A.-M., Boretto, J., Mauvieux, V., LeGall, J. Y., David, V., Pontarotii, P. A continuous restriction map from HLA-E to HLA-F. Structural comparison between different HLA-A haplotypes. Immunogenetics 35: 183–189, 1991
Karlsson, L. and Peterson, P. A. The alpha chain gene of H-2O has an unexpected location in the major histocompatibility complex. J Exp Med 176: 477–483, 1992
Karlsson, L., Surh, C. D., Sprent, J., and Peterson, P. A. A novel class II MHC molecule with limited tissue distribution. Nature 351: 485–488, 1991
Karlsson, L., Surh, C. D., Sprent, J., and Peterson, P. A. An unusual class II molecule. Immunol Today 13: 469–470, 1992
Kasahara, M., Vazquez, M., Sato, K., McKinney, E. C., and Flajnik, M. F. Evolution of the major histocompatibility complex: isolation of class II A cDNA clones from the cartilaginous fish. Proc Natl Acad Sci USA 89: 6688–6692, 1992
Kasahara, M., McKinney, E. C., Flajnik, M. F., and Ishibashi, T. The evolutionary origin of the major histocompatibility complex: polymorphism of class II α chain genes in the cartilaginous fish. Eur J Immunol 23: 2160–2165, 1993
Kato, Y., Salter-Cid, L., Flajnik, M. F., Kasahara, M., Namikawa, C., Sasaki, M., and Nonaka, M. Isolation of the Xenopus complement factor B cDNA and linkage of the gene of the frog MHC. J Immunol, in press
Kaufman, J. and Salomonsen, J. B-G: we know what it is, but what does it do? Immunol Today 13: 1–2, 1992
Kaufman, J., Salomonsen, J., Skjodt, K., and Thorpe, D. Size polymorphism of the chicken major histocompatibility complex-encoded B-G molecules is due to length variation in the cytoplasmic heptad repeat region. Proc Natl Acad Sci USA 87: 8277–8281, 1990
Kaufman, J., Skjodt, K., and Salomonsen, J. The B-G multigene family of the chicken major histocompatibility complex. Crit Rev Immunol 11: 113–143, 1991
Kaufman, J., Skjoedt, K., and Salomonsen, J. The MHC molecules of nonmammalian vertebrates. Immunol Rev 113: 83–117, 1990
Kaufman, J. F., Flajnik, M. F., and DuPasquier, L. Xenopus MHC class II molecules. II. Polymorphism as determined by two-dimentional gel electrophoresis. J Immunol 134: 3258–3264, 1985
Kawaguchi, H., O'hUigin, C., and Klein, J. Evolution of primate C4 and CYP21 genes. In J. Klein and D. Klein (eds.): Molecular Evolution of the Major Histocompatibility Complex, pp. 357–381, Springer, Berlin Heidelberg New York, 1989
Kelly, A., Powis, S. H., Glynne, R., Radley, E., Beck, S., and Trowsdale, J. Second proteasome-related gene in the human MHC class II region. Nature 353: 667–668, 1991
Kelly, A. P., Monaco, J. J., Cho, S., and Trowsdale, J. A new human HLA class II-related locus, DM. Nature 353: 571–573, 1991
Kendall, E., Sargent, C. A., and Campbell, R. D. Human major histocompatibility complex contains a new cluster of genes between the HLA-D and complement C4 loci. Nucleic Acids Res 18: 7251–7257, 1990
Kirisits, M. J., Sawai, H., Kunz, H. W., and Gill, T. J. Multiple TL-like loci in the grc-G/C region of the rat. Immunogenetics 39: 301–315, 1994
Klein, D., Ono, H., O'hUigin, C., Vincek, V., Goldschmidt, T., and Klein, J. Extensive MHC variability in cichlid fishes of Lake Malawi. Nature 364: 330–333, 1993
Klein, J. Natural History of the Major Histocompatibility Complex, John Wiley and Sons, New York, 1986
Klein, J., Takahata, N., and Ayala, F. J. MHC polymorphism and human origins. Sci Am 269: 46–51, 1993
Kroemer, G. Bernot, A., Behar, G. H., Chausse, A. M., Gastinel, L. N, Guilllemot, F., Park, I., Thoraval, P., Zoorob, R., and Auffray, C. Molecular genetics of the chicken MHC: current status and evolutionary aspects. Immunol Rev 113: 119–145, 1990
Kroemer, G., Zoorob, R., and Auffray, C. Structure and expression of a chicken MHC class I gene. Immunogenetics 31: 405–409, 1990
Kronenberg, M., Brines, R., and Kaufman, J. MHC evolution: a long term investment in defense. Immunol Today 15: 4–6, 1994
Lafuse, W. P. Molecular biology of murine MHC class II genes. Crit Rev Immunol 11: 167–194, 1991
Li, H., Gyllensten, U. B., Cui, X., Saiki, R. K., Erlich, H. A., and Arnheim, N. Amplification and analysis of DNA sequences in single human sperm and diploid cells. Nature 335: 414–417, 1988
Lutz, W., Lutz, H., and Gunther, E. Sequence, expression and mapping of a rat Mhc class Ib gene. Immunogenetics 39: 351–354, 1994
Mathis, D. J., Benoist, C., Williams, V. E., Kanter, M., and McDevitt, H. O. Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes. Proc Natl Acad Sci USA 80: 273–277, 1983
Miller, M., Goto, R., Bernot, A., Zoorob, R., Auffray, C., Bumstead, N., and Briles, W. E. Two Mhc class I and two Mhc class II genes map to the chicken Rfp-Y system outside the B complex. Proc Natl Acad Sci USA 91: 4397–4401, 1994
Mombaerts, P., Arnoldi, J., Tonegawa, S., and Kaufman, S. H. Different roles of alpha beta and gamma delta T cells in immunity against an intracellular bacterial pathogen. Nature 365: 53–56, 1993
Monaco, J. J. A molecular model of MHC class I-restricted antigen processing. Immunol Today 13: 173–179, 1992
Morris, P., Shaman, J., Attaya, M., Amaya, M., Goodman, S., Bergman, C., Monaco, J. J., and Mellins, E. An essential role for HLA-DM in antigen presentation by class II major histocompatibility molecules. Nature 368: 551–554, 1994
Nakamura, T., Sekizawa, A., Fujii, T., and Katagiri, C. Cosegregation of the polymorphic C4 with the MHC in the frog, Xenopus laevis. Immunogenetics 23: 181, 1986
Newell, W. R., Trowsdale, J. and Beck, S. MHCDB-database of the human MHC. Immunogenetics 40: 109–115, 1994
Nizetic, D., Figueroa, F., Dembic, Z., Nevo, E., and Klein, J. Major histocompatibility complex gene organization in the mole rat Spalax ehrenbergi: evidence for transfer of function between class II genes. Proc Natl Acad Sci USA 84: 5828–5832, 1987
Okamura, K., Nakanishi, T., Kurosawa, Y., and Hashimoto, K. Expansion of genes that encode MHC class I molecules in cyprinid fishes. J Immunol 151: 188–200, 1993
Ono, H., Figueroa, F., O'hUigin, C., and Klein, J. Cloning of the β2-microglobulin gene in the zebrafish. Immunogenetics 38: 1–10, 1993
Ono, H., Klein, D., Vincek, V., Figueroa, F., O'hUigin, C., Tichy, H., and Klein, J. Major histocompatibility complex class II genes of zebrafish. Proc Natl Acad Sci USA 89: 11886–11890, 1992
Ono, H., O'hUigin, C. Vincek, V., and Klein, J. Exon-intron iroganization of fish major histocompatibility complex class II B genes. Immunogenetics 38: 223–234, 1993
Ono, H., O'hUigin, C., Vincek, V., Stet, R. J. M., Figueroa, F., and Klein, J. New chain-encoding Mhc class II genes in the carp. Immunogenetics 38: 146–149, 1993
Ono, H., O'hUigin, C., Tichy, H., and Klein, J. Major histocompatibility complex variation in two species of cichlid fishes from Lake Malawi. Mol Bol Evol 10 (5) 1060–1072, 1993
Pazderka, F., Longenecker, B. M., Law, G. R. J., and Ruth, R. F. The major histocompatibility complex of the chicken. Immunogenetics 2: 101–130, 1975
Pham-Dinh, D., Mattei, M. G., Nussbaum, J. L., Roussel, G., Pontarotti, P., Roeckel, N., Mather, I. H., Artzt, K., Fischer Lindahl, K., and Dautigny, A. Myelin/oligodendrocyte glycoprotein is a member of a subset of the immunoglobulin superfamily encoded within the major histocompatibility complex. Proc Natl Acad Sci USA 90: 7990–7994, 1993
Plachy, J., Pink, J. R. L., and Hala, K. Biology of the chicken MHC (B complex). Crit Rev Immunol 12: 47–79, 1992
Powis, S. H., Mockridge, I., Kelly, A., Kerr, L.-A., Glynne, R., Gileadi, U., Beck, S., and Trowsdale, J. Polymorphism in a second ABC transporter gene located within the class II region of the human MHC. Proc Natl Acad Sci USA 89: 1463–1467, 1992
Powis, S. H., Tonks, S., Mockridge, I., Kelly, A. P., Bodmer, J. G., and Trowsdale, J. Alleles and haplotypes of the MHC encoded ABC transporters TAP1 and TAP2. Immunogenetics 37: 373–380, 1992
Powis, S. J., Deverson, E. V., Coadwell, W. J., Ciruela, A., Huskisson, N. S., Smith, H., Butcher, G. W., and Howard, J. C. Effect of polymorphism of an MHC-linked transporter on the peptides assembled in a class I molecule. Nature 357: 211–215, 1992
Radley, E., Alderton, R. P., Kelly, A., Trowsdale, J., and Beck, S. Genomic organization of HLA-DMA and HLA-DMB. J Biol Chem 269: 18834–18838, 1994
Rolstad, B., Wonigeit, L., and Vaage, J. T. Alloreactive rat natural killer (NK) cells in vivo and in vitro: the role of the major histocompatibility complex. In B. Rolstad (ed.): Natural Immunity to Normal Hemopoietic Cells, CRC press, Boca Raton, 1993
Salter-Cid, L., Kasahara, M., and Flajnik, M. F., Hsp70 genes are linked to the Xenopus major histocompatibility complex. Immunobenetics 39: 1–7, 1994
Sargent, C. A., Dunham, I., and Campbell, R. D. Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region. EMBO J 8: 2305–2312, 1989
Sato, K., Flajnik, M. F., DuPasquier, L., Katagiri, M., and Kasahara, M. Evolution of the MHC: isolation of class II beta-chain cDNA clones from the amphibian Xenopus laevis. J Immunol 150: 2831–2843. 1993
Satyanarayana, K. and Strominger, J. L. DNA sequences near a meiotic recombinational breakpoint within HLA-DQ region. Immunogenetics 35: 235–240, 1992
Schneider, S., Vincek, V., Tichy, H., Figueroa, F., and Klein, J. MHC class II genes of a marsupial, the red-neckeded wallaby (Macropuss rufogriseus): identification of new gene families. Mol Biol Evol 8: 753–766, 1991
Senger, G., Ragoussis, J., Trowsdale, J., and Sheer, D. Fine mapping of the MHC class II region within 6p21 and evaluation of probe ordering using interphase flourescence in situ hybridization. Cytogenet Cell Genet 61: 49–53, 1993
Shum, B. P., Avila, D., DuPasquier, L., Kasahara, M., and Flajnik, M. F. Isolation of a classical MHC class I cDNA from an amphibian. J Immunol 151: 5376–5386, 1993
Simister, N. E. and Mostov, K. E. An Fc receptor structurally related to MHC class I antigens. Nature 337: 184–187, 1989
Slade, R. W. Limited MHC polymorphism in the southern elephant seal: implications for MHC evolution and marine mammal population biology. Proc R Soc Lond Biol 249: 163–171, 1992
Spies, T., Blanck, G., Bresnahan, M., Sands, J., and Strominger, J. L. A new cluster of genes within the human major histocompatibility complex. Science 243: 214–217, 1989a
Spies, T., Bresnahan, M., and Strominger, J. L. Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B. Proc Natl Acad Sci USA 86: 8955–8958, 1989b
Spring, B., Fonatsch, C., Muller, C., Pawelec, G., Kompf, J., Wernet, P., and Ziegler, A. Refinement of HLA gene mapping with induced B-cell line mutants. Immunogenetics 21: 277–291, 1985
Steinman, L. Connections between the immune system and the nervous system. Proc Natl Acad Sci USA 90: 7912–7914, 1993
Steinmetz, M., Stephan, D., and Fischer Lindahl, K. Gene organization and recombination hotspots in the murine major histocompatibility complex. Cell 44: 895–900, 1986
Stroynowski, I. Molecules related to class I major histocompatibility complex antigens. Annu Rev Immunol 8: 501–530, 1990
Sültmann, H., Mayer, W. E., Figueroa, F., O'hUigin, C., and Klein, J. Zebrafish Mhc class II alpha chain-encoding genes: polymorphism, expression, and function. Immunogenetics 38: 408–420, 1993
Sültmann, H., Mayer, W. E., Figueroa, F., O'hUigin, C., and Klein, J. Organization of Mhc class II B genes in the zebrafish (Brachydanio rerio). Genomics 23: 1–14, 1994
Te Riele, H., Robanus Maandag, E., and Berns, A. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc Natl Acad Sci USA 89: 5128–5132, 1992
Thomsen, M., Neugebauer, M., Arnaud, J., Borot, N., Sevin, A., Baur, M., and Cambon-Thomsen, A. Recombination fractions in the HLA system based on data set “provinces Francaises”: indications of haplotypes-specific recombination rates. Eur J Immunogenet 21: 33–43, 1994
Tonnelle, C., DeMars, R., and Long, E. O. DO beta: a new beta chain gene in HLA-D with a distinct regulation of expression. EMBO J 4: 2839–2847, 1985
Trowsdale, J. Genomic structure and function in the MHC.TIGS 9: 117–122, 1993
Trowsdale, J., Groves, V., and Arnason, A. Limited MHC polymorphism in whales. Immunogenetics 29: 19–24, 1989
Trowsdale, J., Hanson, I., Mockridge, I., Beck, S., Townsend, A., and Kelly, A. Sequences encoded in the class II region of the MHC related to the “ABC” superfamily of transporters. Nature 348: 741–744, 1990
Trowsdale, J. and Kelly, A. The human HLA class II alpha chain gene DZ alpha is distinct from genes in the DP, DQ and DR subregions. EMBO J 4: 2231–2237, 1985
Trowsdale, J. and Powis, S. H. The MHC region-relationship between linkage and function. Curr Opin Genet Dev 2: 492–497, 1992
Uematsu, Y., Kiefer, H., Schulze, R., Fischer Lindahl, K., and Steinmetz, M. Molecular characterization of a meiotic recombinational hotspot enhancing homologous equal crossing-over. EMBO 5: 2123–2129, 1986
Ueyama, H., Niwa, M., Tada, T., Sasaki, M., and Ohkubo, I. Cloning and nucleotide sequence of a human Zn-α2-glycoprotein cDNA and chromosomal assignment of its gene. Biochem Biophys Res Commun 177: 696–703, 1991
Vernet, C., Ribouchon, M. T., Chimini, G., Mauvieux, V., Sidibe, I., and Pontarotti, P. A novel coding sequence belonging to a new multicopy gene family mapping within the human MHC class I region. Immunogenetics 38: 47–53, 1993
Walter, L., Heine, L., Gunther, E. Sequence, expression, and mapping of a rat Mhc class Ib gene. Immunogenetics 39: 351–354, 1994
Wang, C. R. and Fischer Lindahl, K. HMT, encoded by H-2M3, is a neoclassical major histocompatibility class I antigen. Proc Natl Acad Sci USA 90: 2784–2788, 1993
Wang, C. R. and Fischer Lindahl, K. Organization and structure of the H-2M4-M8 class I genes in the mouse MHC. Immunogenetics 38: 258–271, 1993
Wei, H., Fan, W. F., Xu, H., Parimoo, S., Shukla, H., Chaplin, D. D., and Weissman, S. M. Genes in one megabase of the HLA class I region. Proc Natl Acad Sci USA 90: 11870–11874, 1993
Willison, K., Kelly, A., Dudley, K., Goodfellow, P., Spurr, N., Groves, V., Gorman, P., Sheer, D., and Trowsdale, J. The human homologue of the mouse t-complex gene, TCP1, is located on chromosome 6 but is not near the HLA region. EMBO J 6: 1967–1974, 1987
Wright, H., Ballingall, K. T., and Redmond, J. The DY sub-region of the sheep MHC contains an A/B gene pair. Immunogenetics 40: 230–234, 1994
Yu, C. Y., Wu, L. C., Buluwela, L., and Milstein, C. Cosmid cloning and walking to map human CD1 leukocyte differentiation antigen genes. Meth Enzymol 217: 378–400, 1993
Yunis, J. J. Mid-prophase human chromosomes. The attainment of 2000 bands. Hum Genet 56: 293–298, 1981
Zoorob, R., Behar, G., Kroemer, G., and Auffray, C. Organization of a functional chicken clss II B gene. Immunogenetics 31: 179–187, 1990
Zoorob, R., Bernot, A., Renoir, D. M., Choukri, F., and Auffray, C. Chicken major histocompatibility complex class II B genes: analysis of interallelic and interlocus sequence variance. Eur J Immunol 23: 1139–1145, 1993
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Trowsdale, J. “Both man & bird & beast”: comparative organization of MHC genes. Immunogenetics 41, 1–17 (1995). https://doi.org/10.1007/BF00188427
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DOI: https://doi.org/10.1007/BF00188427