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The PiGMaP consortium linkage map of the pig (Sus scrofa)

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Abstract

A linkage map of the porcine genome has been developed by segregation analysis of 239 genetic markers. Eighty-one of these markers correspond to known genes. Linkage groups have been assigned to all 18 autosomes plus the X Chromosome (Chr). As 69 of the markers on the linkage map have also been mapped physically (by others), there is significant integration of linkage and physical map data. Six informative markers failed to show linkage to these maps. As in other species, the genetic map of the heterogametic sex (male) was significantly shorter (∼16.5 Morgans) than the genetic map of the homogametic sex (female) (∼21.5 Morgans). The sex-averaged genetic map of the pig was estimated to be ∼18 Morgans in length. Mapping information for 61 Type I loci (genes) enhances the contribution of the pig gene map to comparative gene mapping. Because the linkage map incorporates both highly polymorphic Type II loci, predominantly microsatellites, and Type I loci, it will be useful both for large experiments to map quantitative trait loci and for the subsequent isolation of trait genes following a comparative and candidate gene approach.

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Authors and Affiliations

  1. Roslin Institute (Edinburgh), EH2 9PS, Roslin, Midlothian, UK

    A. L. Archibald, C. S. Haley, J. F. Brown, S. Couperwhite, H. A. McQueen & D. Nicholson

  2. State University of Ghent, Merelbeke, Belgium

    W. Coppieters & A. Van de Weghe

  3. Institute of Animal Physiology and Genetics, Libechov, Czech Republic

    A. Stratil

  4. The Royal Agricultural and Veterinary University, Copenhagen, Denmark

    A. K. Winterø & M. Fredholm

  5. National Institute of Animal Science, Foulum, Denmark

    N. J. Larsen & V. H. Nielsen

  6. INRA Laboratoire de Génétique Cellulaire, Toulouse, France

    D. Milan, N. Woloszyn, A. Robic, M. Dalens, J. Riquet & J. Gellin

  7. INRA Domaine Pluridisciplinaire du Magneraud, Surgères, France

    J. -C. Caritez & G. Burgaud

  8. INRA Station de Génétique Quantitative et Appliquée, Jouy-en-Josas, France

    L. Ollivier & J. -P. Bidanel

  9. INRA-CEA Laboratoire de Radiobiologie Appliquée, Jouy-en-Josas, France

    M. Vaiman & C. Renard

  10. Universität Hohenheim, Stuttgart, Germany

    H. Geldermann

  11. Universita degli Studi di Bologna, Italy

    R. Davoli

  12. Wageningen Agricultural University, Wageningen, The Netherlands

    D. Ruyter, E. J. M. Verstege & M. A. M. Groenen

  13. Norwegian College of Veterinary Medicine, Oslo, Norway

    W. Davies, B. Høyheim & A. Keiserud

  14. Swedish University of Agricultural Sciences, Uppsala, Sweden

    L. Andersson, H. Ellegren, M. Johansson & L. Marklund

  15. Babraham Institute, Babraham, Cambridge, UK

    J. R. Miller & D. V. Anderson Dear

  16. Department of Genetics, University of Leicester, Leicester, UK

    E. Signer & A. J. Jeffreys

  17. University of Sydney, Sydney, Australia

    C. Moran, P. Le Tissier &  Muladno

  18. Iowa State University, Ames, Iowa, USA

    M. F. Rothschild, C. K. Tuggle, D. Vaske, J. Helm, H. -C. Liu, A. Rahman, T. -P. Yu, R. G. Larson & C. B. Schmitz

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  1. A. L. Archibald
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  2. C. S. Haley
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  29. E. J. M. Verstege
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  31. W. Davies
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  40. E. Signer
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  41. A. J. Jeffreys
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  42. C. Moran
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  43. P. Le Tissier
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  44. Muladno
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  45. M. F. Rothschild
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  46. C. K. Tuggle
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  47. D. Vaske
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  48. J. Helm
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  49. H. -C. Liu
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  50. A. Rahman
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  51. T. -P. Yu
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  52. R. G. Larson
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  53. C. B. Schmitz
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Archibald, A.L., Haley, C.S., Brown, J.F. et al. The PiGMaP consortium linkage map of the pig (Sus scrofa). Mammalian Genome 6, 157–175 (1995). https://doi.org/10.1007/BF00293008

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