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Responses of sympathetic nervous system to cold exposure in vibration syndrome subjects and age-matched healthy controls

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Summary

Plasma norepinephrine and epinephrine in vibration syndrome subjects and age-matched healthy controls were measured for the purpose of estimating the responsibility of the sympathetic nervous system to cold exposure. In preliminary experiment, it was confirmed that cold air exposure of the whole body was more suitable than one-hand immersion in cold water. In the main experiment, 195 subjects were examined. Sixty-five subjects had vibration syndrome with vibration-induced white finger (VWF+ group) and 65 subjects had vibration syndrome without VWF (VWF- group) and 65 controls had no symptoms (control group). In the three groups, plasma norepinephrine levels increased during cold air exposure of whole body at 7° ± 1.5°C. Blood pressure increased and skin temperature decreased during cold exposure. Percent increase of norepinephrine in the VWF+ group was the highest while that in VWF- group followed and that in the control group was the lowest. This whole-body response of the sympathetic nervous system to cold conditions reflected the VWF which are characteristic symptoms of vibration syndrome. Excluding the effects of shivering and a cold feeling under cold conditions, it was confirmed that the sympathetic nervous system in vibration syndrome is activated more than in the controls. These results suggest that vibration exposure to hand and arm affects the sympathetic nervous system.

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References

  • Bovensi M (1986) Cardiovascular responses of vibration-exposed workers to a cold provocation test. Scand J Work Environ Health 12:378–381

    PubMed  Google Scholar 

  • Euler US v (1964) Quantitation of stress by catecholamine analysis. Clin Pharmacol Ther 5:398–404

    Google Scholar 

  • Frankenfaeuser M (1975) Experimental approach to the study of catecholamines and emotion. In: Levi L (ed) Emotion, their parameters and measurement. New York, Raven Press, pp 209–234

    Google Scholar 

  • Futatsuka M, Ueda T (1982) Quantitative observations on thermal and metabolic responses to cold of workers using vibration tools. Int Arch Occup Environ Health 49:213–221

    PubMed  Google Scholar 

  • Itoh N (1984) Studies on the diagnosis of vibration-induced Raynaud's phenomenon of occupational origin (in Japanese with English abstract). J Wakayama Med Soc 35:227–242

    Google Scholar 

  • Lake CR, Chernow B, Feuerstein G, Goldstein DS, Ziegler MG (1984) The sympathetic nervous system in man: its evaluation and the measurement of plasma NE. In: Ziegler MG, Lake CR (eds) Norepinephrine. Williams & Wilkins, Baltimore London, pp 1–26

    Google Scholar 

  • Maruta K, Fujita K, Ito S, Nagatsu T (1984) Liquid chromatography of plasma catecholamines, with electrochemical detection, after treatment with boric acid gel. Clin Chem 30:1271–1273

    Google Scholar 

  • Miyashita K, Shiomi S, Itoh N, Kasamatsu T, Iwata H (1983) Epidemiological study of vibration syndrome in response to total hand-tool operating time. Br J Ind Med 40:92–98

    PubMed  Google Scholar 

  • Nagatsu T, Kojima K (1988) Application of electrochemical detection in high-performance liquid chromatography to the assay of biologically active compounds. Trends Anal Chem 7:21–27

    Article  Google Scholar 

  • Nasu Y, Shingu H, Kishikawa H (1975) Urinary excretion and blood concentration of catecholamine in patients with vibration syndrome (in Japanese with English abstract). Jpn J Traumatol Occup Med 23:267–274

    Google Scholar 

  • O'Malley BP, Cook N, Richerdson A, Barnett B, Rosewoods FD (1984) Circulating catecholamine, thyrotrophin, thyroid hormone and prolactin responses of normal subjects to acute cold exposure. Clin Endocrinol 21:285–291

    Google Scholar 

  • Saito K, Ishizuka S, Azuma K (1986) Plasma and urinary catecholamine concentrations in patients with vibration syndrome before and after hospital treatment. Scand J Work Environ Health 12:262–264

    Google Scholar 

  • Scriven AJI, Brown MJ, Murphy MB, Dollery CT (1984) Changes in blood pressure and plasma catecholamines caused by tyramine and cold exposure. J Cardiovasc Pharmacol 6:954–960

    PubMed  Google Scholar 

  • Une H, Esaki H (1988) Urinary excretion of adrenaline and noradrenaline in lumberjacks with vibration syndrome. Br J Ind Med 45:570–571

    PubMed  Google Scholar 

  • Veselková A, Brodan V, Honzák R (1984) The influence of emotional stress on plasma catecholamines and the effect of blocking agents. In: Usdin E, Kventňanský R, Axelrod J (eds) Stress. The role of catecholamines and other neurotransmitters. Gordon and Breach Publishers, New York, pp 911–918

    Google Scholar 

  • Yahata T, Kuroshima A (1983) Cold-induced changes in plasma catecholamines in men (in Japanese with English abstract). Jpn J Biometeor 20:69–73

    Google Scholar 

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Nakamoto, M. Responses of sympathetic nervous system to cold exposure in vibration syndrome subjects and age-matched healthy controls. Int. Arch Occup Environ Health 62, 177–181 (1990). https://doi.org/10.1007/BF00383595

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  • DOI: https://doi.org/10.1007/BF00383595

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