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Metabolic engineering of sugar catabolism in lactic acid bacteria

  • Metabolism
  • Published:
Antonie van Leeuwenhoek Aims and scope Submit manuscript

Abstract

Lactic acid bacteria are characterized by a relatively simple sugar fermentation pathway that, by definition, results in the formation of lactic acid. The extensive knowledge of traditional pathways and the accumulating genetic information on these and novel ones, allows for the rerouting of metabolic processes in lactic acid bacteria by physiological approaches, genetic methods, or a combination of these two. This review will discuss past and present examples and future possibilities of metabolic engineering of lactic acid bacteria for the production of important compounds, including lactic and other acids, flavor compounds, and exopolysaccharides.

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Authors and Affiliations

  1. Department of Biophysical Chemistry, NIZO, P.O. Box 20, 6710 BA, Ede, The Netherlands

    Willem M. de Vos

  2. Department of Microbiology, Wageningen Agricultural University, The Netherlands

    Willem M. de Vos

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  1. Willem M. de Vos
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de Vos, W.M. Metabolic engineering of sugar catabolism in lactic acid bacteria. Antonie van Leeuwenhoek 70, 223–242 (1996). https://doi.org/10.1007/BF00395934

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