Abstract
The yeasts of patients with oral cancer has been studied before and during Xr-therapy. Gram and PAS smears revealed an increase of yeast-like structures, during treatment, from 56% to 66% of the cases. Before radiotherapy oral yeasts were isolated from 56% of the patients with cancer represented by Candida albicans (30%); C. tropicalis (12%); C. glabrata and C. krusei (4%), besides six other different species (2%). During radiotherapy yeasts were isolated in 72% of the cases, as follow: C. albicans (36%); C. tropicalis (16%); Rhodotorula rubra (6%); C. kefyr; C. krusei and Pichia farinosa (4%), besides other nine species (2%). C. albicans serotype A represented 93% of the isolated samples, before treatment and 88,8% during Xr-therapy.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
All-Doory Y. Laboratory medical mycology. Philadelphia, Leo & Febiger, 1980; 410 p.
Arendorf TM, Walker DM. Oral candidal populations in health and disease. Brit Dent J 1979; 147: 267–72.
Auger P, Dumas C, Joly J. Interrelations of serotypes A and B of C. albicans in mice. Sabouraudia 1983; 21: 173–8.
Bastian RJ, Reade PC. The prevalence of C. albicans in the mouth of tobaco smokers with and without oral mucous membrana keratoses. Oral Surg 1982; 53 (2): 147–51.
Bodey GP. Candidiasis in cancer patients. Proceedings of a Symposium: Candidiasis. A growing concern. Amer J Med 1984; 77 (41): 13–9.
Chen TY, Webster JH. Oral monilia study on patients with head and neck cancer during radiotherapy. Cancer 1974; 34 (2): 246–9.
Cho SY, Choi HY. Opportunistic fungal infection among cancer patients. A 10 year autopsy study. Amer J Clin Path 1979; 72 (4): 617–21.
Clayton JM. Node WC. Observations on the epidemiology of Candida albicans. J Clin Pathol 1966; 19: 76–8.
Difco Laboratories. Detroit. Manual of dehydrated culture media and reagents for microbiological and clinical laboratory procedures. 9th ed., Detroit 1974; p. 239.
Eng RHK, Drehmel R, Smith SM, Goldstein EJ. Saccharomyces cerevisiae infection in man. Sabouraudia 1984; 22 (5): 403–7.
Field EA, Field JK, Martin MV. Does Candida have a role in oral epithelial neoplasia? J med Vet Mycol 1989; 27: 277–94.
Fukazawa Y, Shinoda T, Tsuchiya T. Response and specificity of antibodies for Candida albicans. J Bact 1968; 95: 754–63.
Hasenclever HF, Mitchell WO. Antigenic studies of Candida. I. Observation of two antigenic groups in Candida albicans. J Bact 1961; 82: 570–3.
Hurley R. The pathogenic Candida species and disease caused by Candidas in man. In: Skinner FA, Passmore SM, Davenport RP. Biology and activities of yeasts. London, Academic Press, 1980; pp. 231–48.
Kreger-van Rij NJW. The yeasts: a taxonomic study, 3rd edn, Elsevier, New York 1984; 1082 p.
Lacaz CdaS, Porto E, Martins JEC. Micologia médica. Fungos, actinomicetos e algas de interesse médico. Sã Paulo, Sarvier 1984; 479 p.
Lodder J. The yeasts: a taxonomic study, 2nd edn, North-Nolland, Amsterdam 1970; 1385 p.
Mckenzie DWR. Yeasts from human sources. Sabouraudia 1962; 1: 8–15.
Martin MV, Wilkinson GR. The oral yeast flora of 10-year-old school children. Sabouraudia 1983; 21: 129–35.
McGinnis MR. Laboratory handbook of medical mycology. New York. Academic Press, 1980; 661 p.
Odds FC. Candida and candidosis. Baltimore. Leicester University Press, 1979; 382 p.
Odds FC. Candida and candidosis. London. Saunders 1984; 451 p.
Rafla S, Yang SJ, Meleka F. Changes in cell-immediated immunity in patients undergoing radiotherapy. Cancer 1978; 41: 1076–86.
Rippon JW. Medical mycology. Philadelphia, Saunders 1982; pp. 484–531.
Rodu B, Griffin IL, Grockerman JP. Oral Candidiasis in cancer patients. Sth Med (Bagham, Ala.) 1984; 77 (3): 312–4.
Scully C. Immunology and oral cancer. Brit J Oral Surg 1983; 21 (2): 136–46.
Silva-Hutner M, Cooper BH. Medically important yeast. In: Blair JE, Lennette EH, Truant JP. Manual of clinical microbiology. Baltimore, Williams & Wilkins, 1980; 645 p.
Silverman Jr S, Luangjarmekorn L, Greenspan D. Occurrence or oral candida in irradiated head and neck cancer patients. J Oral Med 1984; 39 (4): 194–196.
Sweet CE, Kaufman L. Application of agglutinins for the rapid and accurate identification of medically important Candida species. Appl Microbiol 1970: 19 (5): 830–6.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Paula, C.R., Sampaio, M.C.C., Birman, E.G. et al. Oral yeasts in patients with cancer of the mouth, before and during radiotherapy. Mycopathologia 112, 119–124 (1990). https://doi.org/10.1007/BF00436507
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00436507