Summary
Furfural, a Maillard reaction product, was found to inhibit growth and alcohol production by Saccharomyces cerevisiae. Furfural concentrations above 1 mg ml−1 significantly decreased CO2 evolution by resuspended yeast cells. Important glycolytic enzymes such as hexokinase, phosphofructokinase, triosephosphate dehydrogenase, aldolase and alcohol dehydrogenase were assayed in presence of furfural. Dehydrogenases appeared to be the most sensitive enzymes and are probably responsible for the observed inhibition of alcohol production and growth.
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Banerjee, N., Bhatnagar, R. & Viswanathan, L. Inhibition of glycolysis by furfural in Saccharomyces cerevisiae . European J. Appl. Microbiol. Biotechnol. 11, 226–228 (1981). https://doi.org/10.1007/BF00505872
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DOI: https://doi.org/10.1007/BF00505872