Abstract
The bone changes in infants with copper deficiency are typified by osteopenia and the symmetrical appearance of sickle-shaped metaphyseal spurs. Four examples are demonstrated and the differential diagnosis is extensively discussed.
References
Ashkenazi A, Levin S, Djaldetti M, Fishel E Benvenisti D (1973) The syndrome of neonatal copper deficiency. Pediatrics 52: 525
Binstadt DH, L'Heureux PR (1978) Rickets as a complication of intravenous hyperalimentation in infants. Pediatr Radiol 7: 211
Boissiere H, Cagnat R, Poissonier M, D'Angely S (1964) Dystrophie osteomalacique du premature. Ann Pediatr 40: 367
Griscom NT, Craig NJ, Neuhauser EBD (1971) Systemic bone disease developing in small premature infants. Pediatrics 48: 883
Heller RM, Kirchner SG, O'Neil JA, Hough AJ, Howard L, Kramer SS, Green LH (1978) Skeletal changes of copper deficiency in infants receiving prolonged total parenteral nutrition. J Pediatr 92: 947
Karpel JT, Paden VH (1972) Copper deficiency in long-term parenteral nutrition. J Pediatr 80: 32
Prasad AS, Oberleas D (1976) Trace elements in human health and disease. Vol I. Academic Press, London, p 366–394
Stanley Ph, Gwinn JL, Sutcliffe J (1976) The osseous abnormalities in Menke's syndrome. Ann Radiol (Paris) 19: 167
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Grünebaum, M., Horodniceanu, C. & Steinherz, R. The radiographic manifestations of bone changes in copper deficiency. Pediatr Radiol 9, 101–104 (1980). https://doi.org/10.1007/BF00977672
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00977672