Abstract
The association between adherence to medical recommendations and health outcomes (physical, role, and social functioning, energy/fatigue, pain, emotional well-being, general health perceptions, diastolic blood pressure, and glycohemoglobin) was examined in a 4-year longitudinal, observational study of 2125 adult patients with chronic medical conditions (hypertension, diabetes, recent myocardial infarction, congestive heart failure) and/or depression. Change score models were evaluated, controlling for disease and comorbidity. Patient adherence was associated minimally with improvement in health outcomes in this study. Only 11 of 132 comparisons showed statistically significant positive effects of adherence on health outcomes. We conclude that
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This work was supported by grants from the Agency for Health Care Policy and Research (Grant HS 06171), the National Institute on Aging, The Robert Wood Johnson Foundation, The Henry J. Kaiser Family Foundation, the National Institute of Mental Health, and the Pew Charitable Trusts, as well as support from RAND and New England Medical Center. The views expressed are those of the authors and do not necessarily represent those of the sponsors or RAND.
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Hays, R.D., Kravitz, R.L., Mazel, R.M. et al. The impact of patient adherence on health outcomes for patients with chronic disease in the medical outcomes study. J Behav Med 17, 347–360 (1994). https://doi.org/10.1007/BF01858007
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DOI: https://doi.org/10.1007/BF01858007