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Cholestasis in patients with amoebic liver abscess

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Abstract

Studies done on patients with amebic liver abscess have revealed a constant hepatic excretory defect for bromsulphthalein (BSP). This was evident from marked lowering of the transport maximum (Tm), with no significant alteration in storage capacity (S) and conjugation. It is inferred that a similar mechanism might contribute to the pathogenesis of jaundice in such patients.

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Authors and Affiliations

  1. From the Division of Hepatic Diseases, Department of Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India

    D. V. Datta MD, PhD (Lond) & P. N. Chhuttani MD (FAMS)

Authors
  1. D. V. Datta MD, PhD (Lond)
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  2. P. N. Chhuttani MD
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Additional information

Supported in part by a grant from the Indian Council of Medical Research.

The authors wish to thank Prof. B. K. Aikat for allowing access to autopsy material of 3 patients; Mr. Gupta for statistical analysis; and Mr. O. P. Nirankari for technical assistance.

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Datta, D.V., Chhuttani, P.N. Cholestasis in patients with amoebic liver abscess. Digest Dis Sci 16, 977–984 (1971). https://doi.org/10.1007/BF02235007

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