Abstract
Urachal neoplasm generally has a poor prognosis, because of long latency period, extravesical progression and pathological predominant pattern of adenocarcinomas. We report a case of recurrent poorly differentiated carcinoma of urachal remnant, which responded well to combination systemic chemotherapy (methotrexate, vinblastine, doxorubicin and cisplatin: M-VAC). Our case was possibly of transitional cell origin. The patient has been symptom-free even 13 months after the first chemotherapy course.
Similar content being viewed by others
References
Sheldon, C. A., Ricardo, C. G., Williams, R. D., Fraley, E. E.: Malignant urachal lesions.J. Urol., 131, 1 (1984).
Rankin, L. F., Allen, G. D., Yuppa, F. R., Pirozzi, M. J., Hajjar, J. R.: Carcinoma of the urachus in an adolescent: A case report.J. Urol., 150, 1472 (1993).
Cornil, C., Reynolds, C. T., Kickham, C. J. E.: Carcinoma of urachus.J. Urol., 98, 93 (1967).
Jacobo, E., Loening, S., Schmidt, J. D., Culp, D. A.: Primary adenocarcinoma of the bladder: A retrospective study of 20 patients.J. Urol., 117, 54 (1977).
Bavendam, T. G., Kramolosky, E. V., Mitros, F. A.: Invasive adenocarcinoma of bladder: Response to cisplatinum, methotrexate, and vinblastine chemotherapy.Urology, 93, 53 (1989).
Logothetis, C. J., Samuels, M. L., Ogden, S.: Chemotherapy for adenocarcinomas of bladder and urachal origin: 5-fluorouracil, doxorubicin, and mitomycin-C.Urology, 26, 252 (1985).
Sternberg, C. N., Yagoda, A., Scher, H. L., Watson, R. C., Ahmed, T., Weiselberg, L. R., Geller, N., Hollander, P. S., Herr, H. W., Sogani, P. C., Morse, M. J., Whitmore, W. F.: Preliminary result of M-VAC (methotrexate, vinblastine, doxorubicin and cisplatin) for transitional cell carcinoma of the urothelium.J. Urol., 133, 403 (1985).
Mostofi, F. K., Sorbin, L. H., Torloni, H.: Histological Typing of Urinary Bladder Tumors. World Health Organization, 1973.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ichiyanagi, O., Sasagawa, I., Suzuki, Y. et al. Successful chemotherapy in a patient with recurrent carcinoma of the urachus. International Urology and Nephrology 30, 569–573 (1998). https://doi.org/10.1007/BF02550547
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02550547