Skip to main content
Log in

p53 Mutations in COMMA-D cells

  • Letter To The Editor
  • Published:
In Vitro Cellular & Developmental Biology - Animal Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Baker, S. J.; Preisinger, A. C.; Jessup, J. M., et al. p53 Gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res. 50:7717–7722; 1990.

    PubMed  CAS  Google Scholar 

  2. Ball, R. K.; Friis, R. R.; Shoenenberger, C. A., et al. Prolactin regulation of beta-casein gene expression and of a cytosolic 120 kd protein in a cloned mouse mammary epithelial cell line. EMBO J. 7:2089–2095; 1988.

    PubMed  CAS  Google Scholar 

  3. Bischoff, J. R.; Casso, D.; Beach, D. Human p53 inhibits growth inSchizosaccharomyces pombe. Mol. Cell. Biol. 12:1405–1411; 1992.

    PubMed  CAS  Google Scholar 

  4. Coles, C.; Condie, A.; Chetty, U., et al. p53 Mutations in breast cancer. Cancer Res. 52:5291–5298; 1992.

    PubMed  CAS  Google Scholar 

  5. Danielson, K. G.; Knepper, J. E.; Kittrell, F. S., et al. Clonal populations of mouse mammary cell line COMMA-D, which retain capability of morphogenesis in vivo. In Vitro Cell. Dev. Biol. 25:535–543; 1989.

    Article  PubMed  CAS  Google Scholar 

  6. Danielson, K. G.; Oborn, C. J.; Durban, E. M., et al. Epithelial mouse mammary cell line exhibiting normal morphogenesisin vivo and functional differentiationin vitro. Proc. Natl. Acad. Sci. USA 81:3756–3760; 1984.

    Article  PubMed  CAS  Google Scholar 

  7. Friedrich, G.; Soriano, P. Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes & Dev. 5:1513–1523; 1991.

    CAS  Google Scholar 

  8. Hainaut, P.; Milner, J. A structural role for metal ions in the “wild-type” conformation of the tumor suppressor protein p53. Cancer Res. 53:1739–1742; 1993.

    PubMed  CAS  Google Scholar 

  9. Jerry, D. J.; Butel, J. S. Direct sequencing of the complete murinep53 cDNA. Comments. United States Biochemical, 19:106, 123–125; 1993.

    Google Scholar 

  10. Jerry, D. J.; Ozbun, M. A.; Kittrell, F. S., et al. Mutations inp53 are frequent in the preneoplastic stage of mouse mammary tumor development. Cancer Res. 53:3374–3381; 1993.

    PubMed  CAS  Google Scholar 

  11. Kittrell, F. S.; Oborn, C. J.; Medina, D. Development of mammary preneoplasiasin vivo from mouse mammary epithelial cell linesin vitro. Cancer Res. 52:1924–1932; 1992.

    PubMed  CAS  Google Scholar 

  12. Kress, S.; Konig, J.; Schweizer, J., et al. p53 Mutations are absent from carcinogen-induced mouse liver tumors but occur in cell lines established from these tumors. Mol. Carcinogen. 6:148–158; 1992.

    Article  CAS  Google Scholar 

  13. Lu, X.; Park, S. H.; Thompson, T. C., et al. ras-Induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation. Cell 70:153–161; 1992.

    Article  PubMed  CAS  Google Scholar 

  14. Medina, D.; Kittrell, F. S. Enhancement of tumorigenicity with morphological progression in a BALB/c preneoplastic outgrowth line. JNCI 79:569–576; 1987.

    PubMed  CAS  Google Scholar 

  15. Medina, D.; Kittrell, F. S.; Oborn, C. J., et al. Growth factor dependency and gene expression in preneoplastic mouse mammary epithelial cells. Cancer Res. 53:665–674; 1993.

    Google Scholar 

  16. Medina, D.; Li, M. L.; Oborn, C. J., et al. Casein gene expression in mouse mammary epithelial cell lines: dependence upon extracellular matrix and cell type. Exp. Cell Res. 172:192–203; 1987.

    Article  PubMed  CAS  Google Scholar 

  17. Medina, D.; Oborn, C. J.; Kittrell, F. S. Properties of mouse mammary epithelial cell lines characterized by in vivo transplantation and in vitro immunocytochemical methods. JNCI 76:1143–1156; 1986.

    PubMed  CAS  Google Scholar 

  18. Ozbun, M. A.; Jerry, D. J.; Kittrell, F. S., et al.p53 Mutations selectedin vivo when mouse mammary epithelial cells form hyperplastic outgrowths are not necessary for establishment of mammary cellsin vitro. Cancer Res. 53:1646–1652; 1993.

    PubMed  CAS  Google Scholar 

  19. Ozbun, M. A.; Medina, D.; Butel, J. S.p53 Mutations in mouse mammary epithelial cells: instability in culture and discordant selection of mutationsin vitro versusin vivo. Cell Growth Differen. 4: 811–819; 1993.

    CAS  Google Scholar 

  20. Sanger, F.; Nicklen, S.; Coulson, A. R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463–5467; 1977.

    Article  PubMed  CAS  Google Scholar 

  21. Schmidhauser, C.; Bissell, M. J.; Myers, C. A., et al. Extracellular matrix and hormones transcriptionally regulate bovine β-casein 5′ sequences in stably transfected mouse mammary cells. Proc. Natl. Acad. Sci. USA 87:9118–9122; 1990.

    Article  PubMed  CAS  Google Scholar 

  22. Thorlacius, S.; Borresen, A.-L.; Eyfjord, J. E. Somatic p53 mutations in human breast carcinomas in an Icelandic population: a prognostic factor. Cancer Res. 53:1637–1641; 1993.

    PubMed  CAS  Google Scholar 

  23. Ziegler, A.; Leffell, D. J.; Kunala, S., et al. Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc. Natl. Acad. Sci. USA 90:4216–4220; 1993.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jerry, D.J., Medina, D. & Butel, J.S. p53 Mutations in COMMA-D cells. In Vitro Cell Dev Biol - Animal 30, 87–89 (1994). https://doi.org/10.1007/BF02631398

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02631398

Keywords

Navigation