Skip to main content
Log in

Vitamin D deficiency rickets at birth in Kuwait

  • Original Article
  • Published:
The Indian Journal of Pediatrics Aims and scope Submit manuscript

Abstract

In the present study vitamin D deficiency rickets has been diagnosed within 24 hrs. of birth. Seventy five full term, otherwise healthy newborns, weighing more than 2.5 kg were born with rachitic rosary. 25-Hydroxyvitamin D was lower than normal in 56 newborns and 15 mothers. Alkaline phosphatase was higher than normal in 26 and radiological changes suggestive of rickets were seen in the wrist X ray of only 14 newborns. Hyperphosphataemia was present in all the newborns. 1,25 dihydroxyvitamin D was markedly increased in six out of ten newborns.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Ford JA, Davidson DC, McIntosh WB, Fyfe WM, Dunnigan MG Neonatal rickets in Asian immigrant population.Br Med J 1973; 3: 211–212.

    PubMed  CAS  Google Scholar 

  2. Moncrieff M, Fadahunsi TQ Congenital rickets due to maternal vitamin D deficiency.Arch Dis child 1974; 49: 810–811.

    PubMed  CAS  Google Scholar 

  3. Serenius F, Elidrissy AHT, Dandona P Vitamin D nutrition in pregnant women at term and in newly born babies in Saudi Arabia.J Clin Pathol 1984; 37: 447–447.

    Article  Google Scholar 

  4. Robinson D, Flynn D, Dandona P. Hyperphosphataemic rickets in an Asian infant.Br Med J 1985; 291: 1318–1319.

    Google Scholar 

  5. Durrigan MG, Paton JPJ, Haases SJ, McNicol GW, Gardner MD, Smith CM. Late rickets and osteomalacia in the Pakistani community in Glasgow.Scott Med J 1961; 7: 159–167.

    Google Scholar 

  6. Okonofua F, Houlder S, Thomas Met al. Parathyroid hormone and neonatal calcium haemostasis: evidence for secondary hyperparathyroidism in the Asian neonate.Metabolism Clin Exper 1986;35: 803–807.

    CAS  Google Scholar 

  7. Gray TK, Lowy W, Lester GE. Vitamin D in pregnancy: the maternal foetal metabolism of vitamin D.Endocr E Rev 1981; 2: 264.

    CAS  Google Scholar 

  8. Cockburn F, Belton NR, Purvis RJet al. Maternal vitamin D intake and mineral metabolism in mothers and their newborn infants.Br Med J 1980; 3: 11–14.

    Google Scholar 

  9. Heckmatt JE, Peacock M, Davies AEet al. Plasma 25-hydroxyvitamin D in pregnant Asian women and their babies.Lancet 1979; ii: 546–548.

    Article  Google Scholar 

  10. Fonseca V, Tongia R, El-Hazmi M, Abu-Aisha H. Exposure to sunlight and vitamin D deficiency in Saudi Arabian women.Postgrad Med J 1984; 60: 19–21.

    Article  Google Scholar 

  11. Steichen JJ, Tsang RC, Gratton TL, Haustra A, DeLuca HF Vitamin D homeostasis in the perinatal period: 1,25 dihydroxyvitamin D in maternal, cord and neonatal blood.N Engl J Med 1980; 302: 315–317.

    Article  PubMed  CAS  Google Scholar 

  12. Weisman Y, Harrel A, Edelstein S, David M, Spirer Z, Goldander A. 1,25-dihydroxy-vitamin D, and 24–25 dihydroxyvitamin D, in vitro synthesis by human decidua and placenta.Nature 1979; 281: 317–318.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Ramavat, L.G. Vitamin D deficiency rickets at birth in Kuwait. Indian J Pediatr 66, 37–43 (1999). https://doi.org/10.1007/BF02752349

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02752349

Key words

Navigation