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Stress fractures in elderly patients

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Abstract

Purpose

The purpose of this study was to investigate specific risk factors, common fracture locations and possible sex-specific differences in elderly patients with stress fractures.

Methods

This analysis enrolled 105 patients (83 women, 22 men) with stress fractures. For the analysis of possible risk factors related to increasing age, data from 82 patients (67 women, 15 men) aged 40 years and older (mean age of 57.4 ± 11.0 years) were compared with that from a younger control group [23 patients (16 women, seven men), mean age 28.4 ± 6.7 years]. Bone mineral density (BMD) was determined using dual-energy X-ray absorptiometry bone densitometry (DXA) and blood samples were taken.

Results

A total of 211 stress fractures were found. Of these, 177 were found in the study group, of which 90.4 % were located in the lower limb. Lumbar and femoral BMD was significantly lower in elderly patients; however, the BMD of most patients was within the osteopenic or normal range. Within the study group, a total of 83.8 % had a vitamin D insufficiency (<30 μg/l); 75.5 % were not engaged in regular physical activity more than once a week. Overweight patients within the study group had significantly more stress fractures compared to normal weight patients (2.6 ± 1.7 vs. 1.9 ± 1.1, p<0.05).

Conclusions

A similar contribution of risk factors has been found for stress fractures in elderly patients and younger controls of the general population. Stress fracture incidence seems to be rather multifactorial and not based on osteoporotic changes alone. A balanced calcium and vitamin D metabolism seems to be of paramount importance for stress fracture prevention in elderly patients.

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References

  1. Mattila VM, Niva M, Kiuru M, Pihlajamaki H (2007) Risk factors for bone stress injuries: a follow-up study of 102,515 person-years. Med Sci Sports Exerc 39:1061–1066

    Article  PubMed  Google Scholar 

  2. Maquirriain J, Ghisi JP (2006) The incidence and distribution of stress fractures in elite tennis players. Br J Sports Med 40:454–459, discussion 459

    Article  PubMed  CAS  Google Scholar 

  3. Burgi AA, Gorham ED, Garland CF, Mohr SB, Garland FC, Zeng K, Thompson K, Lappe JM (2011) High serum 25-hydroxyvitamin D is associated with a low incidence of stress fractures. J Bone Miner Res 26:2371–2377

    Article  PubMed  CAS  Google Scholar 

  4. Valimaki VV, Alfthan H, Lehmuskallio E, Loyttyniemi E, Sahi T, Suominen H, Valimaki MJ (2005) Risk factors for clinical stress fractures in male military recruits: a prospective cohort study. Bone 37:267–273

    Article  PubMed  Google Scholar 

  5. Lappe JM, Stegman MR, Recker RR (2001) The impact of lifestyle factors on stress fractures in female Army recruits. Osteoporos Int 12:35–42

    Article  PubMed  CAS  Google Scholar 

  6. Kiuru MJ, Pihlajamaki HK, Ahovuo JA (2003) Fatigue stress injuries of the pelvic bones and proximal femur: evaluation with MR imaging. Eur Radiol 13:605–611

    PubMed  Google Scholar 

  7. Albisetti W, Perugia D, De Bartolomeo O, Tagliabue L, Camerucci E, Calori GM (2010) Stress fractures of the base of the metatarsal bones in young trainee ballet dancers. Int Orthop 34:51–55

    Article  PubMed  Google Scholar 

  8. Pecina M, Bojanic I, Dubravcic S (1990) Stress fractures in figure skaters. Am J Sports Med 18:277–279

    Article  PubMed  CAS  Google Scholar 

  9. Ivkovic A, Franic M, Bojanic I, Pecina M (2007) Overuse injuries in female athletes. Croat Med J 48:767–778

    Article  PubMed  Google Scholar 

  10. Ivkovic A, Bojanic I, Pecina M (2006) Stress fractures of the femoral shaft in athletes: a new treatment algorithm. Br J Sports Med 40:518–520

    Article  PubMed  CAS  Google Scholar 

  11. Pecina M, Bojanic I, Smoljanovic T, Ivkovic A, Mirkovic M, Jelic M (2011) Surgical treatment of diaphyseal stress fractures of the fifth metatarsal in competitive athletes: long-term follow-up and computerized pedobarographic analysis. J Am Podiatr Med Assoc 101:517–522

    PubMed  Google Scholar 

  12. Pegrum J, Crisp T, Padhiar N (2012) Diagnosis and management of bone stress injuries of the lower limb in athletes. BMJ 344:e2511

    Article  PubMed  Google Scholar 

  13. Daffner RH, Pavlov H (1992) Stress fractures: current concepts. Am J Roentgenol 159:245–252

    CAS  Google Scholar 

  14. Anderson MW, Greenspan A (1996) Stress fractures. Radiology 199:1–12

    PubMed  CAS  Google Scholar 

  15. Fayad LM, Kawamoto S, Kamel IR, Bluemke DA, Eng J, Frassica FJ, Fishman EK (2005) Distinction of long bone stress fractures from pathologic fractures on cross-sectional imaging: how successful are we? AJR Am J Roentgenol 185:915–924

    Article  PubMed  Google Scholar 

  16. Gaeta M, Minutoli F, Scribano E, Ascenti G, Vinci S, Bruschetta D, Magaudda L, Blandino A (2005) CT and MR imaging findings in athletes with early tibial stress injuries: comparison with bone scintigraphy findings and emphasis on cortical abnormalities. Radiology 235:553–561

    Article  PubMed  Google Scholar 

  17. Pepper M, Akuthota V, McCarty EC (2006) The pathophysiology of stress fractures. Clin Sports Med 25:1–16, vii

    Article  PubMed  Google Scholar 

  18. Bennell KL, Malcolm SA, Thomas SA, Reid SJ, Brukner PD, Ebeling PR, Wark JD (1996) Risk factors for stress fractures in track and field athletes. A twelve-month prospective study. Am J Sports Med 24:810–818

    Article  PubMed  CAS  Google Scholar 

  19. McClellan JWr, Vernon BA, White MA, Stamm S and Ryschon KL (2011) Should 25-Hydroxyvitamin D and bone density using DXA be tested in adolescents with lumbar stress fractures of the Pars Interarticularis? J Spinal Disord Tech. doi:10.1097/BSD.0b013e31823f324f

  20. Marx RG, Saint-Phard D, Callahan LR, Chu J, Hannafin JA (2001) Stress fracture sites related to underlying bone health in athletic females. Clin J Sport Med 11:73–76

    Article  PubMed  CAS  Google Scholar 

  21. Teng K (2011) Premenopausal osteoporosis, an overlooked consequence of anorexia nervosa. Cleve Clin J Med 78:50–58

    Article  PubMed  Google Scholar 

  22. Koh JS, Goh SK, Png MA, Kwek EB, Howe TS (2010) Femoral cortical stress lesions in long-term bisphosphonate therapy: a herald of impending fracture? J Orthop Trauma 24:75–81

    Article  PubMed  Google Scholar 

  23. Isaacs JD, Shidiak L, Harris IA, Szomor ZL (2010) Femoral insufficiency fractures associated with prolonged bisphosphonate therapy. Clin Orthop Relat Res 468:3384–3392

    Article  PubMed  Google Scholar 

  24. Shaffer RA, Rauh MJ, Brodine SK, Trone DW, Macera CA (2006) Predictors of stress fracture susceptibility in young female recruits. Am J Sports Med 34:108–115

    Article  PubMed  Google Scholar 

  25. Barrow GW, Saha S (1988) Menstrual irregularity and stress fractures in collegiate female distance runners. Am J Sports Med 16:209–216

    Article  PubMed  CAS  Google Scholar 

  26. Carpintero P, Berral FJ, Baena P, Garcia-Frasquet A, Lancho JL (1997) Delayed diagnosis of fatigue fractures in the elderly. Am J Sports Med 25:659–662

    Article  PubMed  CAS  Google Scholar 

  27. Kaye RA (1998) Insufficiency stress fractures of the foot and ankle in postmenopausal women. Foot & ankle international/American Orthopaedic Foot and Ankle Society [and] Swiss Foot and Ankle Society 19:221

  28. Priemel M, von Domarus C, Klatte TO, Kessler S, Schlie J, Meier S, Proksch N, Pastor F, Netter C, Streichert T, Puschel K, Amling M (2010) Bone mineralization defects and vitamin D deficiency: histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients. J Bone Miner Res 25:305–312

    Article  PubMed  CAS  Google Scholar 

  29. DVO (2011) Guideline 2009 for prevention, diagnosis and therapy of osteoporosis in adults. Osteologie 20:55–74

    Google Scholar 

  30. WHO (1994) Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. Report of a WHO Study Group. World Health Organ Tech Rep Ser 843:1–129

    Google Scholar 

  31. Tenforde AS, Sayres LC, Sainani KL, Fredericson M (2010) Evaluating the relationship of calcium and vitamin D in the prevention of stress fracture injuries in the young athlete: a review of the literature. PM&R 2:945–949

    Article  Google Scholar 

  32. Gennari C (2001) Calcium and vitamin D nutrition and bone disease of the elderly. Public Health Nutr 4:547–560

    Article  PubMed  CAS  Google Scholar 

  33. Ruohola JP, Laaksi I, Ylikomi T, Haataja R, Mattila VM, Sahi T, Tuohimaa P, Pihlajamäki H (2006) Association between serum 25 (OH) D concentrations and bone stress fractures in Finnish young men. J Bone Miner Res 21:1483–1488

    Article  PubMed  CAS  Google Scholar 

  34. Lappe J, Cullen D, Haynatzki G, Recker R, Ahlf R, Thompson K (2008) Calcium and vitamin d supplementation decreases incidence of stress fractures in female navy recruits. J Bone Miner Res 23:741–749

    Article  PubMed  CAS  Google Scholar 

  35. Bischoff-Ferrari H (2009) Vitamin D: what is an adequate vitamin D level and how much supplementation is necessary? Best Pract Res Clin Rheumatol 23:789–795

    Article  PubMed  CAS  Google Scholar 

  36. Givon U, Friedman E, Reiner A, Vered I, Finestone A and Shemer J (2000) Stress fractures in the Israeli defense forces from 1995 to 1996. Clin Orthop Relat Res 373:227–232

    Google Scholar 

  37. Schinke T, Schilling AF, Baranowsky A, Seitz S, Marshall RP, Linn T, Blaeker M, Huebner AK, Schulz A, Simon R, Gebauer M, Priemel M, Kornak U, Perkovic S, Barvencik F, Beil FT, Del Fattore A, Frattini A, Streichert T, Pueschel K, Villa A, Debatin KM, Rueger JM, Teti A, Zustin J, Sauter G, Amling M (2009) Impaired gastric acidification negatively affects calcium homeostasis and bone mass. Nat Med 15:674–681

    Article  PubMed  CAS  Google Scholar 

  38. Yang YX, Lewis JD, Epstein S, Metz DC (2006) Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 296:2947–2953

    Article  PubMed  CAS  Google Scholar 

  39. Law MR, Hackshaw AK (1997) A meta-analysis of cigarette smoking, bone mineral density and risk of hip fracture: recognition of a major effect. BMJ 315:841–846

    Article  PubMed  CAS  Google Scholar 

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The authors state that there is no conflict of interest.

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Correspondence to Michael Amling.

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Stefan Breer and Matthias Krause contributed equally to this work and therefore share first authorship.

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Breer, S., Krause, M., Marshall, R.P. et al. Stress fractures in elderly patients. International Orthopaedics (SICOT) 36, 2581–2587 (2012). https://doi.org/10.1007/s00264-012-1708-1

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  • DOI: https://doi.org/10.1007/s00264-012-1708-1

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