Skip to main content
SpringerLink
Log in

A first-generation porcine whole-genome radiation hybrid map

  • Published:
Mammalian Genome Aims and scope Submit manuscript

Abstract.

A whole-genome radiation hybrid (WG-RH) panel was used to generate a first-generation radiation map of the porcine (Sus scrofa) genome. Over 900 Type I and II markers were used to amplify the INRA-University of Minnesota porcine Radiation Hybrid panel (IMpRH) comprised of 118 hybrid clones. Average marker retention frequency of 29.3% was calculated with 757 scorable markers. The RHMAP program established 128 linkage groups covering each chromosome (n = 19) at a lod ≥ 4.8. Fewer than 10% of the markers (59) could not be placed within any linkage group at a lod score ≥4.8. Linkage group order for each chromosome was determined by incorporating linkage data from the swine genetic map as well as physical assignments. The current map has an estimated ratio of ∼70 kb/cR and a maximum theoretical resolution of 145 kb. This initial map forms a template for establishing accurate YAC and BAC contigs and eventual positional cloning of genes associated with complex traits.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Author information

Authors and Affiliations

  1. Program on Comparative Genomics, College of Veterinary Medicine, University of Minnesota, 1365 Gortner Avenue, St. Paul, Minnesota 55108, USA, , , , , , US

    Rachel J. Hawken, Jeremy Murtaugh, Gail H. Flickinger, Craig W. Beattie, Lawrence B. Schook & Leeson J. Alexander

  2. INRA, Laboratoire de Genetique Cellulaire, 31326 Castanet-Tolosan, France, , , , , , FR

    Martine Yerle, Anne Robic, Denis Milan & Joel Gellin

Authors
  1. Rachel J. Hawken
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jeremy Murtaugh
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Gail H. Flickinger
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Martine Yerle
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Anne Robic
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Denis Milan
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Joel Gellin
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Craig W. Beattie
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Lawrence B. Schook
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Leeson J. Alexander
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Received: 8 January 1999 / Accepted: 13 April 1999

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hawken, R., Murtaugh, J., Flickinger, G. et al. A first-generation porcine whole-genome radiation hybrid map. 10, 824–830 (1999). https://doi.org/10.1007/s003359901097

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/s003359901097

Keywords

Search

Navigation