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Effect of high-energy extracorporeal shock waves on the immature epiphysis in a rabbit model

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Abstract

Introduction

We investigated the effect of high-energy extracorporeal shock wave (ESW) on immature tibial epiphysis in a rabbit model.

Materials and methods

Twenty New Zealand white immature rabbit were used in this study. Animals were divided into two groups and they received 14 kW, 0.6 mJ/mm2, 1,500 or 3,000 shots for three times with an interval of 7 days. After 6 weeks all rabbits were killed. The all tibia epiphysis were assessed by histology. The epiphyseal plaque thickness of right tibiae of the 3,000-shot ESW group was significantly higher than those of the 1,500-shot ESW group and the left tibia epiphyses of the 1,500- and 3,000-shot ESW groups as controls (P < 0.05).

Results

The epiphyseal plaque thickness of right tibiae of the 1,500-shot ESW group was significantly higher than that of the left tibia epiphyses of the 1,500- and 3,000-shot ESW groups as controls (P < 0.05).

Discussion

We demonstrated that high-energy ESW stimulated the growth of immature rabbit epiphysis. The long-term effect of shock wave on the immature rabbit epiphysis deserves further study.

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Acknowledgments

I thank Prof. Ali Cetin and Assist. Prof. Ziynet Cinar for their assistance in the study. Conflict of interest statement: There is no financial support for the study. Ethical Board Review statement: The entire study was approved by the Animal Ethics Committee of Cumhuriyet University School of Medicine, Sivas, Turkey.

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Authors and Affiliations

  1. Department of Orthopaedics and Traumatology, Cumhuriyet University School of Medicine, 58140, Sivas, Turkey

    Hayati Ozturk, Okay Bulut & Zekeriya Oztemur

  2. Department of Histology and Embryology, Cumhuriyet University School of Medicine, 58140, Sivas, Turkey

    Celal Kaloglu

  3. Department of Anesthesiology and Reanimation, Cumhuriyet University School of Medicine, 58140, Sivas, Turkey

    Iclal Ozdemir Kol

Authors
  1. Hayati Ozturk
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  2. Okay Bulut
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  3. Zekeriya Oztemur
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  4. Celal Kaloglu
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  5. Iclal Ozdemir Kol
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Correspondence to Hayati Ozturk.

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Ozturk, H., Bulut, O., Oztemur, Z. et al. Effect of high-energy extracorporeal shock waves on the immature epiphysis in a rabbit model. Arch Orthop Trauma Surg 128, 627–631 (2008). https://doi.org/10.1007/s00402-007-0388-6

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  • DOI: https://doi.org/10.1007/s00402-007-0388-6

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