Abstract
Struma ovarii is a rare form of ovarian neoplasm and its malignant transformation is even rarer. Because of its rarity, there is no consensus about its diagnosis and management in the literature. A 53-year-old woman with left adnexial mass underwent total abdominal hysterectomy with bilateral salpingo-oopherectomy. Postoperatively, she was diagnosed with a malignant struma ovarii. Postoperative thyroid ultrasonography revealed a 0.5-cm solid nodule in the thyroid gland and total thyroidectomy was done. Pathology report was nodular hyperplasia of benign character. She is currently disease-free for 1 year but long-term follow-up with thyroglobulin levels is necessary due to reports of increasing recurrence rates.
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Willemse PH, Oosterhuis JW, Aalders JG, Piers DA, Sleijfer DT, Vermey A, Doorenbos H (1987) Malignant struma ovarii treated by ovariectomy, thyroidectomy, and 131I administration. Cancer 60(2):178–182
Kabukcuoglu F, Baksu A, Yılmaz B, Aktumen A, Evren I (2002) Malignant struma ovarii. Pathol Oncol Res 8(2):145–147
Zakhem A, Aftimos G, Kreidy R, Salem P (1990) Malignant struma ovarii: report of two cases and selected review of the literature. J Surg Oncol 43:61–65
Berghella V, Ngadiman S, Rosenberg H, Hoda S, Zuna R (1997) Malignant struma ovarii. A case report and review of the literature. Gynecol Obstet Invest 43(1):68–72
Devaney K, Synder R, Norris H, Tavassoli F (1993) Proliferative and histologically malignant struma ovarii: a clinicopathologic study of 54 cases. Int J Gynecol Pathol 12(4):333–343
Rosenblum N, LiVolsi V, Edmonds P, Mikuta J (1989) Malignant struma ovarii. Gynecol Oncol 32:224–227
Kostoglou-Athanassiou I, Lekka-Katsouli I, Gogou L, Papagrigoriou L, Chatonides I, Kaldrymides P (2002) Malignant struma ovarii: report of a case and review of the literature. Horm Res 58(1):34–38
Checrallah A, Medlej R, Sade C, Khayat G, Halaby G (2001) Malignant struma ovarii: an unusual presentation. Thyroid 11(9):889–892
DeSimone C, Lele S, Modesitt S (2003) Malignant struma ovarii: a case report and analysis of cases reported in the literature with focus on survival and I131 therapy. Gynecol Oncol 89(3):543–548
Gonzales A, Kaufman RH, Braungardt CD et al (1963) Adenocarcinoma of thyroid arising in struma ovarii (malignant struma ovarii) Report of two cases and review of the literature. Obstet Gynecol 21:567–576
Nogales FF (1995) Germ cell tumours of the ovary. In: Fox H, Wells M (eds) Obstetrical and Gynecological Pathology, 4th edn. Churchill Livingstone, New York, pp 847–896
Szyfelbein WM, Young RH, Scully RE (1995) Struma ovarii simulating ovarian tumors of other types. A report of 30 cases. Am J Surg Pathol 19(1):21–29
Pardo-Mindan FJ, Vazquez JJ (1983) Malignant struma ovarii. Light and electron microscopic study. Cancer 51:337–343
Chan S, Farrell K (2001) Metastatic thyroid carcinoma in the presence of struma ovarii. Med J Aust 175(7):373–374
Dardik RB, Dardik M, Westra W, Montz FJ (1999) Malignant struma ovarii: two case reports and a review of the literature. Gynecol Oncol 73(3):447–451
Makani S, Kim W, Gaba AR (2004) Struma Ovarii with a focus of papillary thyroid cancer: a case report and review of the literature. Gynecol Oncol 94(3):835–839
O’Connell M, Fisher C, Harmer C (1990) Malignant struma ovarii: presentation and management. Br J Radiol 63(749):360–363
Rose PG, Arafah B, Abdul-Karim F (1998) Malignant struma ovarii: recurrence and response to treatment monitored by thyroglobulin levels. Gynecol Oncol 70:425–427
Lubin E, Mechlis-Frish Zata S, Shimoni A, Segal K et al (1994) Serum thyroglobulin and iodine-131 whole-body scan in the diagnosis and assessment of treatment for metastatic differentiated thyroid carcinoma. J Nucl Med 35(2):257–262
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This study was accepted as a poster presentation at the VII International Congress of the Turkish-German Gynecological Association, Antalya, Turkey, 16–20 May 2007.
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Doganay, M., Gungor, T., Cavkaytar, S. et al. Malignant struma ovarii with a focus of papillary thyroid cancer: a case report. Arch Gynecol Obstet 277, 371–373 (2008). https://doi.org/10.1007/s00404-007-0466-6
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DOI: https://doi.org/10.1007/s00404-007-0466-6