Skip to main content
Log in

Indications for penetrating keratoplasty in East China, 1994–2003

  • Clinical Investigation
  • Published:
Graefe's Archive for Clinical and Experimental Ophthalmology Aims and scope Submit manuscript

Abstract

Purpose

To evaluate the indications for penetrating keratoplasty (PKP) and associated procedures in the Eye and ENT Hospital, Fudan University, Shanghai, People’s Republic of China, an eye center in East China and to compare our results with those from previous studies.

Methods

We retrospectively studied the charts of cases who had received PKP in the hospital from 1994 to 2003. The recorded data covered age, sex, and preoperative clinical diagnoses of PKP, and surgical procedures in some cases.

Results

A total of 229 cases received PKP during that period. The number of surgical cases increased dramatically in the last 3 years (2001–2003). The leading indication for PKP was corneal scar (55.9%), which included 44 (19.2%) cases of corneal scar after viral keratitis and 30 (13.1%) cases of corneal scar after chemical/thermal burn. Other indications, in order of decreasing frequency, were bullous keratopathy (12.2%), acute necrotizing/ulcerative keratitis (12.2%), regraft (10.5%), keratoconus (5.7%), and non–Fuchs’ corneal dystrophies (3.8%). Combined procedures were performed on 22 cases. The most three common indications for PKP, corneal scar, bullous keratopathy, acute necrotizing/ulcerative keratitis, showed an increasing frequency in the period of the last 3 years.

Conclusion

The leading indication for PKP was corneal scar, which differed from the conclusion offered by the developed areas in the world, where bullous keratopathy or keratoconus was the case. A similar result was also found in reports from India and Taiwan.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Cosar CB, Sridhar MS, Cohen EJ, Held EL, Rapuano CJ, Raber IM, Laibson PR (2002) Indications for penetrating keratoplasty and associated procedures, 1996–2000. Cornea 21(2):148–151

    Article  PubMed  Google Scholar 

  2. Cürsiefen C, Kuchle M, Naumann GOH (1988) Changing indications for penetrating keratoplasty: histopathology of 1250 corneal buttons. Cornea 17(5):468–470

    Google Scholar 

  3. Dandona L, Ragu K, Janarthanan M, Naduvilath TJ, Shenoy R, Rao GN (1997) Indications for penetrating keratoplasty in India. Ind J Ophthalmol 45(3):163–168

    CAS  Google Scholar 

  4. Dobbins KRB, Price FW Jr, Whitson WE (2000) Trends in the indications for penetrating keratoplasty in the midwestern United States. Cornea 19(6):813–816

    Article  PubMed  CAS  Google Scholar 

  5. Maeno A, Naor J, Lee HM, Hunter WS, Rootman D (2000) Three decades of corneal transplantation: indications and patient characteristics. Cornea 19(1):7–11

    Article  PubMed  CAS  Google Scholar 

  6. Niederkron JY (1999) The immune privilege of corneal allografts. Transplantation 67:1503–1508

    Article  PubMed  Google Scholar 

  7. Sugar A, Sugar J (2000) Techniques in penetrating keratoplasty. A quarter century of development. Cornea 19(5):603–610

    Article  PubMed  CAS  Google Scholar 

  8. Brady SE, Rapuano CJ, Arentsen JJ, Cohen EJ, Laibson PR (1989) Clinical indication for and procedures associated with penetrating keratoplasty, 1983–1988. Am J Ophthalmol 108(2):118–122

    PubMed  CAS  Google Scholar 

  9. Terry MA, Ousley PJ (2003) In pursuit of emmetropia spherial equivalent refraction results with deep lamellar endothelial keratoplasty. Cornea 22(7):619–626

    Article  PubMed  Google Scholar 

  10. Chen WL, Hu FR, Wang IJ (2001) Changing indications for penetrating keratoplasty in Taiwan from 1987 to 1999. Cornea 20(2):141–144

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zhang Chaoran.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Chaoran, Z., Jianjiang, X. Indications for penetrating keratoplasty in East China, 1994–2003. Graefe's Arch Clin Exp Ophthalmo 243, 1005–1009 (2005). https://doi.org/10.1007/s00417-005-1167-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00417-005-1167-0

Keywords

Navigation