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Automated Analysis of Pharyngeal Pressure Data Obtained with High-Resolution Manometry

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Abstract

We present an algorithm developed in MATLAB that can be applied to both normal and disordered swallowing to automatically extract a wide array of measurements from the spatiotemporal plots produced by high-resolution manometry (HRM) of the pharyngeal swallow. The algorithm was developed from data from 12 normal and 3 disordered subjects swallowing 5-ml water boluses. Automated extraction was compared to manual extraction for a subset of seven normal and the three disordered subjects to evaluate algorithm accuracy. Area and line integrals, pressure wave velocity, and pressure gradients during upper esophageal sphincter opening were also measured. Automated extraction showed strong correlations with manual extraction, producing high correlation coefficients in both normal and disordered subjects for maximum velopharyngeal pressure and maximum tongue base pressure. Timing data were also strongly correlated for all variables, including velopharyngeal pressure duration, tongue base pressure duration, and total swallow duration. Preliminary descriptive data on area and line integrals are presented. Our results indicate that the algorithm can effectively extract data automatically from HRM spatiotemporal plots. The efficiency of the algorithm makes it a valuable tool to supplement clinical and research use of HRM.

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References

  1. Kim SM, McCulloch TM, Rim K. Pharyngeal pressure analysis by the finite element method during liquid bolus swallow. Ann Otol Rhinol Laryngol. 2000;109:585–9.

    PubMed  CAS  Google Scholar 

  2. McConnel FM. Analysis of pressure generation and bolus transit during pharyngeal swallowing. Laryngoscope. 1988;98:71–8.

    PubMed  CAS  Google Scholar 

  3. Cook IJ. Normal and disordered swallowing: new insights. Baillieres Clin Gastroenterol. 1991;5:245–67.

    Article  PubMed  CAS  Google Scholar 

  4. McConnel FM, Hood D, Jackson K, O’Connor A. Analysis of intrabolus forces in patients with Zenker’s diverticulum. Laryngoscope. 1994;104:571–81.

    Article  PubMed  CAS  Google Scholar 

  5. Olsson R, Kjellin O, Ekberg O. Videomanometric aspects of pharyngeal constrictor activity. Dysphagia. 1996;11:83–6.

    Article  PubMed  CAS  Google Scholar 

  6. Xue S, Katz PO, Castell JA, et al. Upper esophageal sphincter and pharyngeal manometry: which patients? Gastroenterology. 2000;118:A410 (Abstract).

    Article  Google Scholar 

  7. Logemann JA, Kahrilas PJ, Kobara M, Vakil NB. The benefit of head rotation on pharyngoesophageal dysphagia. Arch Phys Med Rehabil. 1989;70:767–71.

    PubMed  CAS  Google Scholar 

  8. Lazarus C, Logemann JA, Song CW, Rademaker AW, Kahrilas PJ. Effects of voluntary maneuvers on tongue base function for swallowing. Folia Phoniatr Logop. 2002;54:171–6.

    Article  PubMed  Google Scholar 

  9. Boden K, Hallgren A, Witt Hedstrom H. Effects of three different swallow maneuvers analyzed by videomanometry. Acta Radiol. 2006;47:628–33.

    Article  PubMed  CAS  Google Scholar 

  10. Hind JA, Nicosia MA, Roecker EB, Carnes ML, Robbins J. Comparison of effortful and noneffortful swallows in healthy middle-aged and older adults. Arch Phys Med Rehabil. 2001;82:1661–5.

    Article  PubMed  CAS  Google Scholar 

  11. Bulow M, Olsson R, Ekkberg O. Supraglottic swallow, effortful swallow, and chin tuck did not alter hypopharyngeal intrabolus pressure in patients with pharyngeal dysfunction. Dysphagia. 2002;17:197–201.

    Article  PubMed  Google Scholar 

  12. Bulow M, Olsson R, Ekberg O. Videomanometric analysis of supraglottic swallow, effortful swallow, and chin tuck in healthy volunteers. Dysphagia. 1999;14:67–72.

    Article  PubMed  CAS  Google Scholar 

  13. Isberg A, Nilsson ME, Schiratzki H. The upper esophageal sphincter during normal deglutition. A simultaneous cineradiographic and manometric investigation. Acta Radiol Diagn (Stockh). 1985;26:563–8.

    CAS  Google Scholar 

  14. Fox MR, Bredenoord AJ. Oesophageal high-resolution manometry: moving from research into clinical practice. Gut. 2008;57:405–23.

    Article  PubMed  CAS  Google Scholar 

  15. Takasaki K, Umeki H, Enatsu K, Tanaka F, Sakihama N, Kumagami H, Takahashi H. Investigation of pharyngeal swallowing function using high-resolution manometry. Laryngoscope. 2008;118:1729–32.

    Article  PubMed  Google Scholar 

  16. McCulloch T, Hoffman MR, Ciucci MR. High resolution manometry of pharyngeal swallow pressure events associated with head turn and chin tuck. Ann Otol Rhinol Laryngol. 2010;119(6):369–76.

    PubMed  Google Scholar 

  17. Umeki H, Takasaki K, Enatsu K, Tanaka F, Kumagami H, Takahashi H. Effects of a tongue-holding maneuver during swallowing evaluated by high-resolution manometry. Otolaryngol Head Neck Surg. 2009;141:119–22.

    Article  PubMed  Google Scholar 

  18. Takasaki K, Umeki H, Kumagami H, Takahashi H. Influence of head rotation on upper esophageal sphincter pressure evaluated by high-resolution manometry system. Otolaryngol Head Neck Surg. 2010;142:214–7.

    Article  PubMed  Google Scholar 

  19. Hoffman MR, Ciucci MR, Mielens JD, Jiang JJ, McCulloch TM. Pharyngeal swallow adaptations to bolus volume measured with high resolution manometry. Laryngoscope. 2010;120(12):2367–73.

    Article  PubMed  Google Scholar 

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Acknowledgments

This study was supported by a grant from the Department of Surgery, University of Wisconsin School of Medicine and Public Health. The authors thank Dr. Glen Leverson for his assistance with the statistical analysis.

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Authors and Affiliations

  1. Department of Surgery, Division of Otolaryngology – Head and Neck Surgery, University of Wisconsin School of Medicine and Public Health, Box 7375, Clinical Science Center – H4, 600 Highland Avenue, Madison, WI, 53792-7375, USA

    Jason D. Mielens, Matthew R. Hoffman, Michelle R. Ciucci, Jack J. Jiang & Timothy M. McCulloch

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  1. Jason D. Mielens
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  2. Matthew R. Hoffman
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  3. Michelle R. Ciucci
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  4. Jack J. Jiang
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  5. Timothy M. McCulloch
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Correspondence to Timothy M. McCulloch.

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Mielens, J.D., Hoffman, M.R., Ciucci, M.R. et al. Automated Analysis of Pharyngeal Pressure Data Obtained with High-Resolution Manometry. Dysphagia 26, 3–12 (2011). https://doi.org/10.1007/s00455-010-9320-2

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  • DOI: https://doi.org/10.1007/s00455-010-9320-2

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