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Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency

  • Clinical nephrology / Original Article
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Pediatric Nephrology Aims and scope Submit manuscript

Abstract 

A patient with homozygous factor H deficiency presented with hemolytic uremic syndrome (HUS) at the age of 7 months. After a 2-year period of stability, renal failure and erythrocyte fragmentation recurred between the age of 3 and 4 years. Fresh frozen plasma infusions allowed renal function to be improved and erythrocyte fragmentation to be stopped. Withdrawal of plasma therapy led to a relapse of the biological signs of HUS.

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Authors and Affiliations

  1. Service de Néphrologie Pédiatrique, Hôpital Armand-Trousseau, 26 avenue du Dr. Arnold-Netter, 75571 Paris cedex 12, France e-mail: georges.deschenes@trs.ap-hop-paris.fr Tel.: +33-1-44736032, Fax: +33-1-44736663, , , , , , FR

    Sylvie Nathanson & G. Deschênes

  2. Hôpital Européen Georges Pompidou, Service d"Immunologie Biologique, 20 rue Leblanc, 75015 Paris, France, , , , , , FR

    Véronique Frémeaux-Bacchi

Authors
  1. Sylvie Nathanson
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  2. Véronique Frémeaux-Bacchi
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  3. G. Deschênes
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Additional information

Received: 18 April 2000 / Revised: 18 August 2000 / Accepted: 21 August 2000

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Nathanson, S., Frémeaux-Bacchi, V. & Deschênes, G. Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency. Pediatr Nephrol 16, 554–556 (2001). https://doi.org/10.1007/s004670100609

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  • DOI: https://doi.org/10.1007/s004670100609

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