Original articleCorrelation between inflammatory cytokines released from the lumbar facet joint tissue and symptoms in degenerative lumbar spinal disorders
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Controlled immobilization-traction based on intervertebral stability is conducive to the regeneration or repair of the degenerative disc: an in vivo study on the rat coccygeal model
2019, Spine JournalCitation Excerpt :Previous clinical studies have confirmed that height loss of a degenerative IVD may affect the function of articular processes [40–42]. These processes are accompanied by a narrow joint space, poor joint faces, hyperplasia of the joint, and instability of the spine [40–42]. In addition, instability can lead to accelerated disc degeneration, which can lead to pain and neurologic dysfunction [13].
Effect of Pulsed Radiofrequency Therapy on Chronic Refractory Atlanto-Occipital Joint Pain
2018, World NeurosurgeryCitation Excerpt :In addition, electric fields induced by PRF have anti-inflammatory effects. Previous studies by Igarashi et al.21 and Sluijter et al.18 demonstrated that PRF stimulation reduced the levels of inflammatory cytokines, such as interleukin-1β, tumor necrosis factor-α, and interleukin-6. Several studies reported that intra-articular PRF reduced serum C-reactive protein and cytokine levels.18,22,23
Cytokine and chemokine profile changes in patients with lower segment lumbar degenerative spondylolisthesis
2017, International Journal of SurgeryCitation Excerpt :This study investigated the involvement of inflammatory mediators in lumbar DS pathogenesis through the study of IVD and FJB tissues obtained from patient suffering from lumbar DS and healthy controls during a multiorgan procurement procedure. Prior studies proposed that degenerative lumbar disorders, including lumbar DS, involves complex interactions in the immune system to mediate inflammation, remodeling, and IVDD, and these interactions function in the development of low-back and/or radicular pain [8–14]. The molecular mechanisms and pathways implicated in these processes are not completely understood.
Scoping review to develop common data elements for lumbar spinal stenosis
2017, Spine Journal