Activities of lysozyme and salivary peroxidase in unstimulated whole saliva in relation to plaque and gingivitis scores in healthy young males

Abstract 

The purpose of the present investigation was to study the suitability of the salivary activity of lysozyme and salivary peroxidase for monitoring the inflammatory state of the gingiva. Salivary peroxidase and lysozyme activities in resting whole saliva were measured in a group of 140 male subjects (aged 18–30 years). A full mouth, clinical assessment of the plaque index (PI) and the sulcus bleeding index (SBI) was made and gingival crevicular fluid (GCF) flow was measured at teeth 16, 12, 24, 36, 32 and 44 with the Periotron 6000. There were no significant differences in the mean values of lysozyme and salivary peroxidase activities between groups with different PI, SBI and GCF flow values. Statistically significant correlations were found among the clinical parameters, with SBI and PI showing the strongest relation (r=0.47). The correlation between GCF flow and PI was higher (r=0.43) than the correlation between GCF flow and SBI (r=0.20). However, there were no statistically significant correlations between the activities of salivary peroxide and lysozyme and the clinical measures of gingival health.