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Cytomegalovirus-induced interstitial pneumonitis in a patient with dermatomyositis

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Abstract

Dermatomyositis (DM) patients might present with pulmonary involvement as the first manifestation or during the follow-up period. It is sometimes difficult to determine whether the clinical manifestations related with pulmonary involvement are due to DM or to an infectious process. We report a case of DM patient who developed interstitial pneumonitis induced by cytomegalovirus (CMV) while receiving immunosuppressive treatment. To the best of our knowledge, this is the second report in the literature of interstitial pneumonitis secondary to CMV infection in a patient with DM.

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References

  1. Tazelaar HD, Viggiano RW, Pickersgill J, Colby TV (1990) Interstitial lung disease in polymyositis and dermatomyositis. Am Rev Respir Dis 141:727–733

    PubMed  CAS  Google Scholar 

  2. Drew WL (1992) Cytomegalovirus infection inpatients with AIDS. Clin Infect Dis 14:608–615

    PubMed  CAS  Google Scholar 

  3. Weller TH (1971) The cytomegaloviruses: ubiquitous agents with protean clinical manifestations: II. N Engl J Med 285:267–274

    Article  PubMed  CAS  Google Scholar 

  4. Meyers JD, Flournoy N, Thomas E (1986) Risk factors for cytomegalovirus infection after human bone marrow transplantation. J Infect Dis 153:478–488

    PubMed  CAS  Google Scholar 

  5. van der Bij W, Schirm J, Torensma R, van Son WJ, Tegzess AM, The TH (1988) Comparison between viremia and antigenemia for detection of cytomegalovirus in blood. J Clin Microbiol 26:2531–2535

    PubMed  Google Scholar 

  6. Nishi K, Myoh S, Bandoh T et al (1992) An autopsy case of dermatomyositis associated with interstitial pneumonia probably due to cytomegalovirus infection. Nihon Kyobu Shikkan Gakkai Zasshi 30:1975–1980

    PubMed  CAS  Google Scholar 

  7. Hashimoto Y, Nawata Y, Kurasawa K et al (1995) Investigation of EB virus and cytomegalovirus in rapidly progressive interstitial pneumonitis in polymyositis/dermatomyositis by in situ hybridization and polymerase chain reaction. Clin Immunol Immunopathol 77:298–306

    Article  PubMed  CAS  Google Scholar 

  8. Leung AN, Gosselin MV, Napper CH et al (1999) Pulmonary infections after bone marrow transplantation: clinical and radiographic findings. Radiology 210:699–710

    PubMed  CAS  Google Scholar 

  9. Boumpas DT, Chrousos GP, Wilder RL, Cupps TR, Balow JE (1993) Glucocorticoid therapy for immune-mediated diseases: basic and clinical correlates. Ann Intern Med 119:1198–1208

    PubMed  CAS  Google Scholar 

  10. Dowling JN, Saslow AR, Armstrong JA, Ho M (1976) Cytomegalovirus infection in patients receiving immunosuppressive therapy for rheumatologic disorders. J Infect Dis 133:399–408

    PubMed  CAS  Google Scholar 

  11. Goodgame RW (1993) Gastrointestinal cytomegalovirus disease. Ann Intern Med 119:924–935

    PubMed  CAS  Google Scholar 

  12. Syrjanen S, Leimola-Virtanen R, Schmidt-Westhausen A, Reichart PA (1999) Oral ulcers in AIDS patients frequently associated with cytomegalovirus (CMV) and Epstein–Barr virus (EBV) infections. J Oral Pathol Med 28:204–209

    Article  PubMed  CAS  Google Scholar 

  13. Lloid ME, Schubert MM, Myerson D, Bowden R, Meyers JD, Hackman RC (1994) Cytomegalovirus infection of the tongue following marrow transplantation. Bone Marrow Transplant 14:99–104

    PubMed  CAS  Google Scholar 

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Correspondence to Cengiz Korkmaz.

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Kaşifoğlu, T., Korkmaz, C. & Özkan, R. Cytomegalovirus-induced interstitial pneumonitis in a patient with dermatomyositis. Clin Rheumatol 25, 731–733 (2006). https://doi.org/10.1007/s10067-005-0062-8

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