Abstract:
Central nervous system involvement is rarely an initial presenting manifestation of Behçet’s disease (BD). We report the case of a 33-year-old man with recurrent attacks of fever, oral mucosal ulcers, deep venous thrombosis, diplopia, vertigo and headache. Sequential brain magnetic resonance imaging (MRI) scans showed fluctuating lesions of the brain stem, mesencephalon and thalamus. F-18-fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) revealed hypometabolism at the parieto-occipital cortex at both sides and the brain stem. Treatment with prednisone and cyclosporine A led to a complete remission and normalisation of MRI and FDG-PET lesions. The present case illustrates the difficulty in the differential diagnosis of early neuro-BD.
Similar content being viewed by others
Author information
Authors and Affiliations
Additional information
Received: 26 October 1999 / Accepted: 23 December 1999
Rights and permissions
About this article
Cite this article
Weiner, S., Otte, A., Schumacher, M. et al. Neuro-Behçet’s Syndrome in a Patient not Fulfilling Criteria for Behçet’s Disease: Clinical Features and Value of Brain Imaging. Clin Rheumatol 19, 231–234 (2000). https://doi.org/10.1007/s100670050164
Issue Date:
DOI: https://doi.org/10.1007/s100670050164