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The Influence of Hormonal Contraception on Mood and Sexual Interest among Adolescents

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Abstract

Mood and sexual interest changes are commonly cited reasons for discontinuing hormonal contraceptives. Data, however, are inconsistent and limited to adult users. We examined associations of hormonal contraceptive use with mood and sexual interest among adolescents. We recruited 14–17-year-old women from primary care clinics and followed them longitudinally for up to 41 months. Participants completed face-to-face interviews quarterly and two 12-week periods of daily diary collection per year. On daily diaries, participants recorded positive mood, negative mood, and sexual interest. We classified 12-week diary periods as “stable OCP use,” “non-use,” “initiated use,” “stopped use,” and “DMPA use” based on self-report of oral contraceptive pill (OCP) use and depot medroxyprogesterone acetate (DMPA) use from medical charts. Diary periods were the unit of analysis. Participants could contribute more than one diary period. We analyzed data using linear models with a random intercept and slope across weeks in a diary period, an effect for contraceptive group, and an adjustment for age at the start of a diary period. Mean weekly positive mood was higher in diary periods characterized by stable OCP use, compared to other groups. Mean weekly negative mood was lower in diary periods characterized by stable OCP use and higher in periods characterized by DMPA use. Periods characterized by stable OCP use additionally showed less mood variation than other groups. Changes in mood among adolescent hormonal contraceptive users differed from those anticipated for adult users. Attention to adolescent-specific changes in mood and sexual interest may improve contraceptive adherence.

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References

  • Arnett, J. J. (1999). Adolescent storm and stress, reconsidered. American Psychologist, 54, 317–326.

    Article  PubMed  CAS  Google Scholar 

  • Bancroft, J., & Rennie, D. (1993). The impact of oral contraceptives on the experience of perimenstrual mood, clumsiness, food craving and other symptoms. Journal of Psychosomatic Research, 37, 195–202.

    Article  PubMed  CAS  Google Scholar 

  • Bancroft, J., & Sartorius, N. (1990). The effects of oral contraceptives on well-being and sexuality. Oxford Reviews of Reproductive Biology, 12, 57–92.

    PubMed  CAS  Google Scholar 

  • Civic, D., Scholes, D., Ichikawa, L., LaCroix, A. Z., Yoshida, C. K., Ott, S. M., et al. (2000). Depressive symptoms in users and non-users of depot medroxyprogesterone acetate. Contraception, 61, 385–390.

    Article  PubMed  CAS  Google Scholar 

  • Compas, B. E., Ey, S., & Grant, K. E. (1993). Taxonomy, assessment, and diagnosis of depression during adolescence. Psychological Bulletin, 114, 323–344.

    Article  PubMed  CAS  Google Scholar 

  • Cromer, B. A., Smith, R. D., Blair, J. M., Dwyer, J., & Brown, R. T. (1994). A prospective study of adolescents who choose among levonorgestrel implant (Norplant), medroxyprogesterone acetate (Depo-Provera), or the combined oral contraceptive pill as contraception. Pediatrics, 94, 687–694.

    PubMed  CAS  Google Scholar 

  • Davis, A. R., & Castaño, P. M. (2004). Oral contraceptives and libido in women. Annual Review of Sex Research, 15, 297–320.

    PubMed  Google Scholar 

  • Fortenberry, J. D., Temkit, M., Tu, W., Graham, C. A., Katz, B. P., & Orr, D. P. (2005). Daily mood, partner support, sexual interest, and sexual activity among adolescent women. Health Psychology, 24, 252–257.

    Article  PubMed  Google Scholar 

  • Furstenberg, F. F., Shea, J., Allison, P., Herceg-Baron, R., & Webb, D. (1983). Contraceptive continuation among adolescents attending family planning clinics. Family Planning Perspectives, 15, 211–214, 216–217.

    Google Scholar 

  • Grady, W. R., Billy, J. O., & Klepinger, D. H. (2002). Contraceptive method switching in the United States. Perspectives on Sexual and Reproductive Health, 34, 135–145.

    Article  PubMed  Google Scholar 

  • Graham, C. A., Ramos, R., Bancroft, J., Maglaya, C., & Farley, T. M. (1995). The effects of steroidal contraceptives on the well-being and sexuality of women: A double-blind, placebo-controlled, two-centre study of combined and progestogen-only methods. Contraception, 52, 363–369.

    Article  PubMed  CAS  Google Scholar 

  • Gupta, N., O’Brien, R., Jacobsen, L. J., Davis, A., Zuckerman, A., Supran, S., et al. (2001). Mood changes in adolescents using depot-medroxyprogesterone acetate for contraception: A prospective study. Journal of Pediatric and Adolescent Gynecology, 14, 71–76.

    Article  PubMed  CAS  Google Scholar 

  • Hatcher, R. A., Trussell, J., Stewart, F., Nelson, A. L., Cates, W., Guest, F., et al. (2004). Contraceptive technology (18th rev. ed.). New York: Ardent Media, Inc.

    Google Scholar 

  • Katz, B. P., Fortenberry, J. D., Tu, W., Harezlak, J., & Orr, D. P. (2001). Sexual behavior among adolescent women at high risk for sexually transmitted infections. Sexually Transmitted Diseases, 28, 247–251.

    PubMed  CAS  Google Scholar 

  • Kaunitz, A. M. (1999). Long-acting hormonal contraception: Assessing impact on bone density, weight, and mood. International Journal of Fertility and Women’s Medicine, 44, 110–117.

    PubMed  CAS  Google Scholar 

  • Kay, C. R. (1984). The Royal College of General Practitioners’ Oral Contraception Study: Some recent observations. Clinics in Obstetrics and Gynaecology, 11, 759–786.

    PubMed  CAS  Google Scholar 

  • Kramer, C. Y. (1956). Extension of multiple range tests to group means with unequal numbers of replications. Biometrics, 12, 307–310.

    Article  Google Scholar 

  • Matson, S. C., Henderson, K. A., & McGrath, G. J. (1997). Physical findings and symptoms of depot medroxyprogesterone acetate use in adolescent females. Journal of Pediatric and Adolescent Gynecology, 10, 18–23.

    PubMed  CAS  Google Scholar 

  • Oinonen, K. A., & Mazmanian, D. (2001). Effects of oral contraceptives on daily self-ratings of positive and negative affect. Journal of Psychosomatic Research, 51, 647–658.

    Article  PubMed  CAS  Google Scholar 

  • Oinonen, K. A., & Mazmanian, D. (2002). To what extent do oral contraceptives influence mood and affect? Journal of Affective Disorders, 70, 229–240.

    Article  PubMed  CAS  Google Scholar 

  • Rosenthal, S. L., Cotton, S., Ready, J. N., Potter, L. S., & Succop, P. A. (2002). Adolescents’ attitudes and experiences regarding levonorgestrel 100 mcg/ethinyl estradiol 20 mcg. Journal of Pediatric and Adolescent Gynecology, 15, 301–305.

    Article  PubMed  CAS  Google Scholar 

  • Sanders, D., Warner, P., Backstrom, T., & Bancroft, J. (1983). Mood, sexuality, hormones and the menstrual cycle. I. Changes in mood and physical state: Description of subjects and method. Psychosomatic Medicine, 45, 487–501.

    PubMed  CAS  Google Scholar 

  • Sanders, S. A., Graham, C. A., Bass, J. L., & Bancroft, J. (2001). A prospective study of the effects of oral contraceptives on sexuality and well-being and their relationship to discontinuation. Contraception, 64, 51–58.

    Article  PubMed  CAS  Google Scholar 

  • Slap, G. B. (1981). Oral contraceptives and depression: Impact, prevalence and cause. Journal of Adolescent Health Care, 2, 53–64.

    Article  CAS  Google Scholar 

  • Smiler, A. P., Ward, L. M., Caruthers, A., & Merriwether, A. (2005). Pleasure, empowerment, and love: Factors associated with a positive first coitus. Sexuality Research and Social Policy: Journal of NSRC, 2, 41–55.

    Article  Google Scholar 

  • Tolman, D. L. (2002). Dilemmas of desire: Teenage girls talk about sexuality. Cambridge, MA: Harvard University Press.

    Google Scholar 

  • Warner, P., & Bancroft, J. (1988). Mood, sexuality, oral contraceptives and the menstrual cycle. Journal of Psychosomatic Research, 32, 417–427.

    Article  PubMed  CAS  Google Scholar 

  • Warner, P., Bancroft, J., Dixson, A., & Hampson, M. (1991). The relationship between perimenstrual depressive mood and depressive illness. Journal of Affective Disorders, 23, 9–23.

    Article  PubMed  CAS  Google Scholar 

  • Westhoff, C. (2003). Depot-medroxyprogesterone acetate injection (Depo-Provera): A highly effective contraceptive option with proven long-term safety. Contraception, 68, 75–87.

    Article  PubMed  CAS  Google Scholar 

  • Westhoff, C., Wieland, D., & Tiezzi, L. (1995). Depression in users of depo-medroxy-progesterone acetate. Contraception, 51, 351–354.

    Article  PubMed  CAS  Google Scholar 

  • Woods, J. L., Shew, M. L., Tu, W., Ofner, S., Ott, M. A., & Fortenberry, J. D. (2006). Patterns of oral contraceptive pill-taking and condom use among adolescent contraceptive pill users. Journal of Adolescent Health, 39, 381–387.

    Article  PubMed  Google Scholar 

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Correspondence to Mary A. Ott.

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Ott, M.A., Shew, M.L., Ofner, S. et al. The Influence of Hormonal Contraception on Mood and Sexual Interest among Adolescents. Arch Sex Behav 37, 605–613 (2008). https://doi.org/10.1007/s10508-007-9302-0

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  • DOI: https://doi.org/10.1007/s10508-007-9302-0

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