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Breast cancer characteristics and outcomes among Hispanic Black and Hispanic White women

  • Epidemiology
  • Published:
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Abstract

Evaluating breast cancer outcomes specific to Hispanics of different race (e.g. Hispanic Black, Hispanic White) may further explain variations in the burden of breast cancer among Hispanic women. Using data from the SEER 17 population-based registries, we evaluated the association between race/ethnicity and tumor stage, hormone receptor status, and breast cancer-specific mortality. The study cohort of 441,742 women, aged 20–79, who were diagnosed with primary invasive breast cancer between January 1, 1992 and December 31, 2008, included 44,246 Hispanic whites, 622 Hispanic Blacks, 44,797 non-Hispanic Blacks and 352,077 non-Hispanic whites. Hispanic black, Hispanic white and non-Hispanic black women had a 1.5–2.5 fold greater risk of presenting with stage IV breast cancer compared to non-Hispanic whites. All groups were significantly more likely than non-Hispanic whites to be diagnosed with ER+/PR− (1.1–1.5 fold increase) or ER−/PR− (1.4–2.2 fold increase) breast cancer. Hispanic black, Hispanic white and non-Hispanic black women had a 10–50 % greater risk of breast cancer-specific mortality compared to non-Hispanic whites. Our findings underscore the breast cancer disparities that continue to exist for Hispanic and black women, overall, as well as between Hispanic women of different race. These disparities highlight the factors that may lead to the poor outcomes observed among Hispanic and black women diagnosed with breast cancer, and for which targeted strategies aimed at reducing breast cancer disparities could be developed.

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Acknowledgments

This research was supported, in part, by the National Institutes of Health, National Cancer Institute, Center for Population Health and Health Disparities (Grant no.: 5 P50 CA148143) and the Fogarty International Center (Grant no.: RO3 TW007900).

Conflicts of interest

The authors have no conflicts of interest to disclose.

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Authors and Affiliations

  1. Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, P.O. Box 19024 (M3-B232), Seattle, WA, 98109, USA

    Matthew P. Banegas & Christopher I. Li

  2. Department of Health Services, School of Public Health, University of Washington, P.O. Box 357660, Seattle, WA, 98195, USA

    Matthew P. Banegas

  3. Department of Epidemiology, School of Public Health, University of Washington, P.O. Box 357236, Seattle, WA, 98195, USA

    Christopher I. Li

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  1. Matthew P. Banegas
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Correspondence to Matthew P. Banegas.

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Banegas, M.P., Li, C.I. Breast cancer characteristics and outcomes among Hispanic Black and Hispanic White women. Breast Cancer Res Treat 134, 1297–1304 (2012). https://doi.org/10.1007/s10549-012-2142-1

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