We propose a 4-D representation of RNA secondary structures. The four-dimensional representation resolves structures’ degeneracy and avoids loss of information and the limitation that different structures correspond the same plot set (or presentation). The RNA pseudoknpts also can be represented as four-dimensional representations. Based on this representation, we outline an approach to compute the similarities between six RNA secondary structures for illustrating the utility of our approach.
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Bafna V, Muthukrisnan S, Ravi R, (1995). Comput. Sci. 937: 1
Corpet F, Michot B, (1995). Comput. Appl. Biosci 10: 389
Le S.Y, Nussinov R, Mazel J.V, (1989). Comput. Biomed. Res 22: 461
Le S.Y, Onens J, Nussinov R, Chen J.H, Shapiro B, Mazel J.R, (1989). Comput. Biomed 5: 205
Shapiro B, (1998). Comput. Appl. Biosci 4(3): 387
Shapiro B, Zhang K, (1990). Comput. Appl. Biosci. 6(4): 309
Zhang K, in: Pro. IEEE. Internat. Joint Symp On Intelligence and Sytems Rockviue, Maryland, May, (1998) 126–132
Gan H.H, Pasquali S, Schlick T, (2003). Nuclei Acids Res 31: 2926
Liao B, Wang T, (2004). J. Biomol. struct. Dyn. 21: 827
Liao B, Ding K.Q, Wang T.M, (2005). J. Biomol. Struct. Dyn 22: 455
Liao B, Wang T.M, (2005). Mol. Simulat 14: 1063
Bai F.L, Zhu W, Wang T.M, (2005). Chem. Phys. Lett. 408: 258
Yao Y.H, Nan X.Y, Wang T.M, (2005). J. Comput. Chem. 26: 1339
Zhu W, Liao B, Ding K.Q, (2005). J. Mole. Struct. THEOCHEM. 757: 193
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Liao, B., Zhu, W. & Li, P. On a four-dimensional representation of RNA secondary structures. J Math Chem 42, 1015–1022 (2007). https://doi.org/10.1007/s10910-006-9156-z
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DOI: https://doi.org/10.1007/s10910-006-9156-z