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Multiple anthelmintic resistance on a goat farm in Hawassa (southern Ethiopia)

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Abstract

A study was conducted to determine the presence of anthelmintic resistance on Hawassa University goat farm in southern Ethiopia. The 180 goats were stratified by age and sex and randomly assigned to treatment groups (albendazole, tetramisole and ivermectin and untreated control). Each treatment group included 15 goats and treatments were administered according to weight of each goat with 7.5 mg/kg bw albendazole, 22.5 mg/kg bw tetramisole and 0.2 mg/kg bw ivermectin dose rates recommended by scientists. Faecal samples were collected on day 0 before treatment, and again on day 12 post treatment. Efficacy of all the drugs was assessed on day 12 post treatment by faecal egg count reduction test (FECRT). Multiple anthelmintic resistance in Haemonchus spp. against albendazole, tetramisole and ivermectin was recorded in all age categories of the goats. Likewise, Trichostrongylus/Teladorsagia spp. showed resistance against ivermectin. Coprocultures from all pre- and post-treatments revealed the predominance of Haemonchus spp. Resistance against anthelmintics is attributed to the high frequency of treatment and low dosage of treatment practices on the farm. Large scale studies, however, are needed to assess the current status of anthelmintic resistance against the most commonly used anthelmintics in different agroecology, species of animals and management systems in Ethiopia.

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Abbreviations

CL:

confidence limit

EPG:

eggs per gram of faeces

FEC:

faecal egg count

FECRT:

faecal egg count reduction test

L3 :

third stage infective larvae

WAAVP:

World Association for the Advancement of Veterinary Parasitology

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Acknowledgements

The authors thank the management personels of Hawassa University goat farm and staff members of Parasitology laboratory of department of Animal and Range Sciences of Hawassa University for their cooperation and allowing to use the available facilities. The authors gratefully acknowledge Prof. Feseha G/ab, head of donkey sancutruy of Ethiopia, for his revision of the english language of the manuscript.

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Authors and Affiliations

  1. Department of Parasitology, Faculty of Veterinary Medicine, Addis Ababa University, P.O. Box 34, Debre Zeit, Ethiopia

    Bersissa Kumsa

  2. Department of Animal and Range Sciences, Hawassa College of Agriculture, Hawassa University, P.O. Box 5, Hawassa, Ethiopia

    Girma Abebe

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  1. Bersissa Kumsa
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  2. Girma Abebe
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Correspondence to Bersissa Kumsa.

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Kumsa, B., Abebe, G. Multiple anthelmintic resistance on a goat farm in Hawassa (southern Ethiopia). Trop Anim Health Prod 41, 655–662 (2009). https://doi.org/10.1007/s11250-008-9237-z

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