Skip to main content

Advertisement

Log in

A Comparative Study of Mortality Among Puerto Rican Injection Drug Users in East Harlem, New York, and Bayamon, Puerto Rico

  • Published:
Journal of Urban Health Aims and scope Submit manuscript

Abstract

Drug users have been found to be at high risk of mortality but the mortality experience of Hispanic drug users remains understudied. This study assessed mortality among Puerto Rican injection drug users (IDUs) in New York City (NY), and in Puerto Rico (PR). Study subjects were 637 IDUs from NY and 319 IDUs from PR. Mortality was ascertained using data from the National Death Index. Annual mortality rate of the NY cohort was 1.3 per 100 person years compared to the PR cohort with a rate of 4.8. Compared to the Hispanic population of New York City, the standardized mortality ratio (SMR) of the NY cohort was 4.4. Compared to the population of Puerto Rico, the SMR of the PR cohort was 16.2. The four principal causes of death were: NY—HIV/AIDS (50.0%), drug overdoses (13.3%), cardiovascular conditions (13.3%), and pulmonary conditions (10.0%); PR—HIV/AIDS (37.0%), drug overdoses (24.1%), sepsis (13.0%), and homicide (11.1%). Modeling time to death using Cox proportional hazards regression, the relative risk of mortality of the PR cohort as compared to the NY cohort was 9.2. The other covariates found to be significantly associated with time to death were age, gender, education, social isolation, intoxication with alcohol, and HIV seropositivity. The large disparity in mortality rates found in this study suggests that health disparities research should be expanded to identify intra-group disparities. Furthermore, these results point to an urgent need to reduce excess mortality among IDUs in Puerto Rico.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1

Similar content being viewed by others

References

  1. Vlahov D, Wang C, Galai N, et al. Mortality risk among new onset injection drug users. Addiction. 2004;99:946–954.

    Article  PubMed  Google Scholar 

  2. Goedert JJ, Fung MW, Felton S, Battjes RJ, Engels EA. Cause-specific mortality associated with HIV and HTL-VII infections among injecting drug users in the USA. AIDS. 2001;15:1295–1302.

    Article  PubMed  CAS  Google Scholar 

  3. Tyndall MW, Craib KJ, Currie S, Li K, O'Shaughnessy MV, Schechter MT. Impact of HIV infection on mortality in a cohort of injection drug users. J Acquir Immune Defic Syndr. 2001;28:351–357.

    PubMed  CAS  Google Scholar 

  4. Hulse GK, English DR, Milne E, Holman CD. The quantification of mortality resulting from the regular use of illicit opiates. Addiction. 1999;94:221–229.

    Article  PubMed  CAS  Google Scholar 

  5. Copeland L, Budd J, Robertson JR, Elton RA. Changing patterns in causes of death in a cohort of injecting drug users, 1980–2001. Arch Intern Med. 2004;164:1214–1220.

    Article  PubMed  Google Scholar 

  6. Marzuk PM, Tardiff K, Leon AC, et al. Poverty and fatal accidental drug overdoses of cocaine and opiates in New York City: an ecological study. Am J Drug Alcohol Abuse. 1997;23:221–228.

    PubMed  CAS  Google Scholar 

  7. Kawachi I, Kennedy BP, Lochner K, Prothrow-Stith D. Social capital, income inequality, and mortality. Am J Public Health. 1997;87:1491–1498.

    PubMed  CAS  Google Scholar 

  8. Whitman S, Murphy J, Cohen M, Sherer R. Marked declines in human immunodeficiency virus-related mortality in Chicago in women, African Americans, Hispanics, young adults, and injection drug users, from 1995 through 1997. Arch Intern Med. 2000;160:365–369.

    Article  PubMed  CAS  Google Scholar 

  9. Bargagli AM, Sperati A, Davoli M, Forastiere F, Perucci CA. Mortality among problem drug users in Rome: an 18-year follow-up study, 1980–97. Addiction. 2001;96:1455–1463.

    Article  PubMed  CAS  Google Scholar 

  10. Wahren CA, Brandt L, Allebeck P. Has mortality in drug addicts increased? A comparison between two hospitalized cohorts in Stockholm. Int J Epidemiol. 1997;26:1219–1226.

    Article  PubMed  CAS  Google Scholar 

  11. Zaccarelli M, Gattari P, Rezza G, et al. Impact of HIV infection on non-AIDS mortality among Italian injecting drug users. AIDS. 1994;8:345–350.

    Article  PubMed  CAS  Google Scholar 

  12. Galli M, Musicco M. Mortality of intravenous drug users living in Milan, Italy: role of HIV-1 infection. COMCAT Study Group. AIDS. 1994;8:1457–1463.

    Article  PubMed  CAS  Google Scholar 

  13. Darke S, Zador D. Fatal heroin ‘overdose’: a review. Addiction. 1996;91:1765–1772.

    Article  PubMed  CAS  Google Scholar 

  14. Sperry K. An epidemic of intravenous narcoticism deaths associated with the resurgence of black tar heroin. J Forensic Sci. 1988;33:1156–1162.

    PubMed  CAS  Google Scholar 

  15. Darke S, Hall W, Weatherburn D, Lind B. Fluctuations in heroin purity and the incidence of fatal heroin overdose. Drug Alcohol Depend. 1999;54:155–161.

    Article  PubMed  CAS  Google Scholar 

  16. Appel PW, Joseph H, Richman BL. Causes and rates of death among methadone maintenance patients before and after the onset of the HIV/AIDS epidemic. Mt Sinai J Med. 2000;67:444–451.

    PubMed  CAS  Google Scholar 

  17. Galea S, Ahern J, Tardiff K, et al. Racial/ethnic disparities in overdose mortality trends in New York City, 1990–1998. J Urban Health. 2003;80:201–211.

    PubMed  Google Scholar 

  18. Delva J, Wallace JM Jr, O'Malley PM, Bachman JG, Johnston LD, Schulenberg JE. The epidemiology of alcohol, marijuana, and cocaine use among Mexican American, Puerto Rican, Cuban American, and other Latin American eighth-grade students in the United States: 1991–2002. Am J Public Health. 2005;95:696–702.

    Article  PubMed  Google Scholar 

  19. Alvarez J, Olson BD, Jason LA, Davis MI, Ferrari JR. Heterogeneity among Latinas and Latinos entering substance abuse treatment: findings from a national database. J Subst Abuse Treat. 2004;26:277–284.

    Article  PubMed  Google Scholar 

  20. Ortega AN, Rosenheck R, Alegria M, Desai RA. Acculturation and the lifetime risk of psychiatric and substance use disorders among Hispanics. J Nerv Ment Dis. 2000;188:728–735.

    Article  PubMed  CAS  Google Scholar 

  21. Selik, R.M. Comparison of Rates of Death Due to HIV Disease among U.S. Hispanics of Different National Origins in 2000. Paper presented at the National HIV Prevention Conference, Atlanta, Georgia, July 2003.

  22. Montoya, ID, Bell, DC, Richard, AJ, Carlson, JW, and Trevino, RA. Estimated HIV risk among Hispanics in a national sample of drug users. J Acquir Immune Defic Syndr. 1999;21:21–50.

    Google Scholar 

  23. Ortega AN, Rosenheck R, Alegria M, Desai RA. Acculturation and the lifetime risk of psychiatric and substance use disorders among Hispanics. J Nerv Ment Dis. 2000;188:728–735

    Article  PubMed  CAS  Google Scholar 

  24. Wallace JM Jr, Bachman JG, O'Malley PM, Johnston LD, Schulenberg JE, Cooper SM. Tobacco, alcohol, and illicit drug use: racial and ethnic differences among U.S. high school seniors, 1976–2000. Public Health Rep. 2002;117(Suppl 1):S67–S75.

    PubMed  Google Scholar 

  25. Centers for Disease Control and Prevention. HIV AIDS Surveill Rep, 2004. Vol. 16. Atlanta: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention; 2005.

    Google Scholar 

  26. Pan American Health Organization. AIDS Surveillance in the Americas. Pan American Health Organization, Washington DC, June 2002.

  27. Puerto Rico Department of Health. AIDS Surveillance Report. Puerto Rico Department of Health, San Juan, Puerto Rico, 2005.

  28. Diaz T, Buehler JW, Castro KG, Ward JW. AIDS trends among Hispanics in the United States. Am J Public Health. 1993;83:504–509.

    PubMed  CAS  Google Scholar 

  29. Deren, S, Robles, RR, Andia, JF, Colón, HM, Kang, S-Y, Perlis, T. Trends in HIV seroprevalence and needle sharing among Puerto Rican drug injectors in Puerto Rico and New York: 1992–1999. J Acquir Immune Defic Syndr. 2001;26:164–169.

    Article  PubMed  CAS  Google Scholar 

  30. Robles RR, Matos TD, Colon HM, et al. Mortality among Hispanic drug users in Puerto Rico. P R Health Sci J. 2003;22:369–376.

    PubMed  Google Scholar 

  31. Deren S, Oliver-Velez D, Finlinson A, et al. Integrating qualitative and quantitative methods: comparing HIV-related risk behaviors among Puerto Rican drug users in Puerto Rico and New York. Subst Use Misuse. 2003;38:1–24.

    Article  PubMed  CAS  Google Scholar 

  32. Oliver-Velez D, Finlinson HA, Deren S, et al. Mapping the air-bridge locations: the application of ethnographic mapping techniques to dual-site study of HIV risk behavior determinants in East Harlem, New York and Bayamón, Puerto Rico. Hum Organ. 2002;61:262–276.

    Google Scholar 

  33. Radloff LS. A CES-D scale: a self-report depression scale for research in the general population. J Appl Meas. 1977;1:385–401.

    Google Scholar 

  34. Vera M, Alegria M, Freeman D, Robles RR, Rios R, Rios CF. Depressive symptoms among Puerto Ricans: island poor compared with residents of the New York City area. Am J Epidemiol. 1991;134:502–10.

    PubMed  CAS  Google Scholar 

  35. Colon HM, Robles RR, Deren S, et al. Between-city variation in frequency of injection among Puerto Rican injection drug users: East Harlem, New York, and Bayamon, Puerto Rico. J Acquir Immune Defic Syndr. 2001,27:405–413.

    PubMed  CAS  Google Scholar 

  36. Bureau of Vital Statistics. Summary of Vital Statistics 2002: The City of New York. New York City Department of Health and Mental Hygiene; 2003.

  37. Division de Estadisticas. Informe anual de estadísticas vitales de Puerto Rico. Departamento de Salud, San Juan, Puerto Rico; 1995.

    Google Scholar 

  38. Sahai H, Khurshid A. Statistics in Epidemiology: Methods, Techniques, and Applications. New York: CRC, 1996.

    Google Scholar 

  39. Cox DR, Oakes DO. Analysis of Survival Data. London: Chapman & Hall; 1984.

    Google Scholar 

  40. Colon HM, Reyes JC, Matos TE, Robles RR. Drug induced deaths is Puerto Rico 1990–2000: Evidence of a public health emergency. Poster presented at the 131 Annual Meeting of the American Public Health Association, November 2003.

  41. Federal Bureau of Investigations. Uniform Crime Report: Crime in the United Sates, 2001. Washington, District of Columbia: U.S. Department of Justice; 2002.

    Google Scholar 

  42. Mayor AM, Gómez MA, Ríos-Olivares E, Hunter-Mellado R. Mortality trends of HIV-infected patients after introduction of highly active antiretroviral therapy: analysis of a cohort of 3,322 HIV-infected persons. Ethn Dis. 2005;15(Suppl 5):57–62.

    Google Scholar 

  43. Appel PW, Joseph H, Richman BL. Causes and rates of death among methadone maintenance patients before and after the onset of the HIV/AIDS epidemic. Mt Sinai J Med. 2000;67:444–451.

    PubMed  CAS  Google Scholar 

  44. Friedman LN, Williams MT, Singh TP, Frieden TR. Tuberculosis, AIDS, and death among substance abusers on welfare in New York City. N Engl J Med. 1996;334:828–833.

    Article  PubMed  CAS  Google Scholar 

  45. Deren S, Kang SY, Colon HM, Andia JF, Robles RR. HIV incidence among high-risk Puerto Rican drug users: a comparison of East Harlem, New York, and Bayamon, Puerto Rico. J Acquir Immune Defic Syndr. 2004;36:1067–1074.

    PubMed  Google Scholar 

  46. Robles RR, Matos TD, Colon HM, et al. Determinants of health care use among Puerto Rican drug users in Puerto Rico and New York City. Clin Infect Dis. 2003;37(Suppl 5):S392–S403.

    Article  PubMed  Google Scholar 

  47. Gossop M, Stewart D, Treacy S, Marsden J. A prospective study of mortality among drug misusers during a 4-year period after seeking treatment. Addiction. 2002;97:39–47.

    Article  PubMed  Google Scholar 

  48. O'Driscoll PT, McGough J, Hagan H, Thiede H, Critchlow C, Alexander ER. Predictors of accidental fatal drug overdose among a cohort of injection drug users. Am J Public Health. 2001;91:984–987.

    Article  PubMed  Google Scholar 

  49. Piketty C, Castiel P, Giral P, et al. Lack of legal income is strongly associated with an increased risk of AIDS and death in HIV-infected injecting drug users. AIDS Care. 1999;11:429–36.

    Article  PubMed  CAS  Google Scholar 

  50. Weatherby NL, Needle R, Cesari H, Booth RE. Validity of self-reported drug use among injection drug users and crack cocaine users recruited through street outreach. Eval Program Plann. 1994;17:347–355.

    Article  Google Scholar 

  51. Dowling GS, Johnson ME, Fisher DG, Needle R. Reliability of drug users' self-reported HIV risk behaviors and validity of self-reported recent drug use. Assessment. 1994;1:383–392.

    Google Scholar 

  52. Buka SL. Disparities in health status and substance use: ethnicity and socioeconomic factors. Public Health Rep. 2002;117(Suppl 1):S118–S125.

    PubMed  Google Scholar 

  53. Zambrana RE, Carter-Pokras O. Health data issues for Hispanics: implications for public health research. J Health Care Poor Underserved. 2001;12:20–34.

    PubMed  CAS  Google Scholar 

  54. Palacio H, Shiboski CH, Yelin EH, Hessol NA, Greenblatt RM. Access to and utilization of primary care services among HIV-infected women. J Acquir Immune Defic Syndr. 1999;21:293–300.

    PubMed  CAS  Google Scholar 

  55. Solomon L, Stein M, Flynn C, et al. Health services use by urban women with or at risk of HIV-1 infection: the HIV epidemiology research study (HERS). J Acquir Immune Defic Syndr Hum Retrovirol. 1998;17:253–261.

    PubMed  CAS  Google Scholar 

  56. Sanders-Phillips K. The ecology of urban violence: its relationship to health promotion behaviors in low-income black and Latino communities. Am J Health Promot. 1996;10:308–317.

    PubMed  CAS  Google Scholar 

  57. Bauer HM, Rodriguez MA, Quiroga SS, Flores-Ortiz YG. Barriers to health care for abused Latina and Asian immigrant women. J Health Care Poor Underserved. 2000;11:33–44.

    PubMed  CAS  Google Scholar 

Download references

AcknowledgEments

This study was funded by the National Institute On Drug Abuse, Grant DA10425. The authors also wish to express their appreciation to the Demographic Registry of the Puerto Rico Department of Health, the National Death Index of the National Center for Health Statistics, and the Office of Vital Statistics, New York City Department of Health, for their collaboration in obtaining the mortality data.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hector Manuel Colon.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Colon, H.M., Deren, S., Robles, R.R. et al. A Comparative Study of Mortality Among Puerto Rican Injection Drug Users in East Harlem, New York, and Bayamon, Puerto Rico. J Urban Health 83, 1114–1126 (2006). https://doi.org/10.1007/s11524-006-9088-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11524-006-9088-8

Keywords

Navigation