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Office-Based Management of Opioid Dependence with Buprenorphine: Clinical Practices and Barriers

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Abstract

Background

Buprenorphine is a safe, effective and underutilized treatment for opioid dependence that requires special credentialing, known as a waiver, to prescribe in the United States.

Objective

To describe buprenorphine clinical practices and barriers among office-based physicians.

Design

Cross-sectional survey.

Participants

Two hundred thirty-five office-based physicians waivered to prescribe buprenorphine in Massachusetts.

Measurements

Questionnaires mailed to all waivered physicians in Massachusetts in October and November 2005 included questions on medical specialty, practice setting, clinical practices, and barriers to prescribing. Logistic regression analyses were used to identify factors associated with prescribing.

Results

Prescribers were 66% of respondents and prescribed to a median of ten patients. Clinical practices included mandatory counseling (79%), drug screening (82%), observed induction (57%), linkage to methadone maintenance (40%), and storing buprenorphine notes separate from other medical records (33%). Most non-prescribers (54%) reported they would prescribe if barriers were reduced. Being a primary care physician compared to a psychiatrist (AOR: 3.02; 95% CI: 1.48–6.18) and solo practice only compared to group practice (AOR: 3.01; 95% CI: 1.23–7.35) were associated with prescribing, while reporting low patient demand (AOR: 0.043, 95% CI: 0.009–0.21) and insufficient institutional support (AOR: 0.37; 95% CI: 0.15–0.89) were associated with not prescribing.

Conclusions

Capacity for increased buprenorphine prescribing exists among physicians who have already obtained a waiver to prescribe. Increased efforts to link waivered physicians with opioid-dependent patients and initiatives to improve institutional support may mitigate barriers to buprenorphine treatment. Several guideline-driven practices have been widely adopted, such as adjunctive counseling and monitoring patients with drug screening.

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Acknowledgements

The authors would like to thank Amber Jamanka, Jacqueline Ashba, and Andrew Hanchett for data management and analysis contributions, Colleen Labelle, RN, for assistance with survey design and feedback on the manuscript, and Courtney Pierce for assistance in preparing the manuscript. This project was funded by the Massachusetts Department of Public Health. Parts of this work were presented at the Society of General Internal Medicine New England regional meeting, 23 March 2007, the College on Problems in Drug Dependence annual meeting, 19 June 2007, and the Association for Medical Education and Research in Substance Abuse annual meeting, 9 November 2007.

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Correspondence to Alexander Y. Walley MD, MSc.

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Walley, A.Y., Alperen, J.K., Cheng, D.M. et al. Office-Based Management of Opioid Dependence with Buprenorphine: Clinical Practices and Barriers. J GEN INTERN MED 23, 1393–1398 (2008). https://doi.org/10.1007/s11606-008-0686-x

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  • DOI: https://doi.org/10.1007/s11606-008-0686-x

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