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Nanoceria as antioxidant: Synthesis and biomedical applications

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Abstract

The therapeutic application of nanomaterials has been a focus of numerous studies in the past decade. Due to its unique redox properties, cerium oxide (ceria) is finding widespread use in the treatment of medical disorders caused by the reactive oxygen intermediates (ROI). The radical-scavenging role of ceria nanoparticles (nanoceria) have been established, as well as the autocatalytic ability of nanoceria to regenerate under various environmental conditions. The synthesis of nanoceria in biocompatible media has also been reported along with cell viability in order to determine the potential use of nanoceria in biomedical applications.

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Authors and Affiliations

  1. Surface Engineering and Nanotechnology Facility, Advanced Materials Processing and Analysis Center, Department of Mechanical Materials and Aerospace Engineering, University of Central Florida, Orlando, Florida, USA

    A. S. Karakoti

  2. Joint Department of Biomedical Engineering, University of North Carolina and North Carolina State University, Raleigh, North Carolina, USA

    N. A. Monteiro-Riviere, R. Aggarwal & R. J. Narayan

  3. Center for Chemical Toxicology Research and Pharmacokinetics, North Carolina State University, Raleigh, North Carolina, USA

    N. A. Monteiro-Riviere

  4. USDA ARS Market Quality and Handling Research Unit, Department of food, Bioprocessing and Nutrition Sciences, North Carolina State University, Raleigh, North Carolina, USA

    J. P. Davis

  5. Department of Molecular Biology and Microbiology, Burnett College of Biomedical Sciences, University of Central Florida, Orlando, USA

    W. T. Self

  6. Department of Ophthalmology, Dean A. McGee Eye Institute, University of Oklahoma, Oklahoma City, Oklahoma, USA

    J. McGinnis

  7. Surface Engineering and Nanotechnology Facility, Advanced Materials Processing and Analysis Center, Department of Mechanical Materials and Aerospace Engineering, University of Central Florida, Orlando, USA

    S. Seal

  8. Nanoscience and Technology Center, University of Central Florida, Orlando, USA

    S. Seal

Authors
  1. A. S. Karakoti
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  2. N. A. Monteiro-Riviere
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  3. R. Aggarwal
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  4. J. P. Davis
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  5. R. J. Narayan
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  6. W. T. Self
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  7. J. McGinnis
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  8. S. Seal
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Correspondence to R. J. Narayan.

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Karakoti, A.S., Monteiro-Riviere, N.A., Aggarwal, R. et al. Nanoceria as antioxidant: Synthesis and biomedical applications. JOM 60, 33–37 (2008). https://doi.org/10.1007/s11837-008-0029-8

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  • DOI: https://doi.org/10.1007/s11837-008-0029-8

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