Skip to main content
SpringerLink
Log in

Bacillus Phytases: Present Scenario and Future Perspectives

  • Published:
Applied Biochemistry and Biotechnology Aims and scope Submit manuscript

Abstract

Phytases are a special class of phosphatases that catalyze the sequential hydrolysis of phytate to less-phosphorylated myo-inositol derivatives and inorganic phosphate. Bacillus phytases, which exhibit their desirable activity profile under neutral pH, higher thermal stability, and strict substrate specificity for the calcium–phytate complex, have considerable potential in commercial and environmental applications. This review describes recent findings concerning the production, biochemical properties, molecular characteristics, and expression of Bacillus phytases. Several potential applications of the Bacillus phytases in animal nutrition, human health, and synthesis of lower myo-inositol phosphates are also summarized.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cheryan, M. (1980). Critical Reviews in Food Science and Nutrition, 13, 297–335.

    Article  CAS  Google Scholar 

  2. Brinch-Pedersen, H., & Hatzack, F. (2006). Current Analytical Chemistry, 2, 421–430.

    Article  CAS  Google Scholar 

  3. Lei, X. G., & Porres, J. M. (2003). Biotechnology Letters, 25, 1787–1794.

    Article  CAS  Google Scholar 

  4. Cao, L., Wang, W. M., Yang, C. T., Yang, Y., Diana, J., Yakupitiyage, A., et al. (2007). Enzyme and Microbial Technology, 40, 497–507.

    Article  CAS  Google Scholar 

  5. Greiner, R., & Konietzny, U. (2006). Food Technology and Biotechnology, 44, 125–140.

    CAS  Google Scholar 

  6. da Silva, L. G., Trugo, L. C., Terzi, S. C., & Couri, S. (2005). Process Biochemistry, 40, 951–954.

    Article  CAS  Google Scholar 

  7. Dvorakova, J., Kopecky, J., Havlicek, V., & Kren, V. (2000). Folia Microbiologica, 45, 128–132.

    Article  CAS  Google Scholar 

  8. Haefner, S., Knietsch, A., Scholten, E., Braun, J., Lohscheidt, M., & Zelder, O. (2005). Applied Microbiology and Biotechnology, 68, 1–10.

    Article  CAS  Google Scholar 

  9. Mullaney, E. J., & Ullah, A. H. J. (2003). Biochemical and Biophysical Research Communications, 312, 179–184.

    Article  CAS  Google Scholar 

  10. Kim, Y. O., Kim, H. K., Bae, K. S., Yu, J. H., & Oh, T. K. (1998). Enzyme and Microbial Technology, 22, 2–7.

    Article  CAS  Google Scholar 

  11. Gulati, H. K., Chadha, B. S., & Saini, H. S. (2007). Journal of Industrial Microbiology & Biotechnology, 34, 91–98.

    Article  CAS  Google Scholar 

  12. Choi, Y. M., Noh, D. O., Cho, S. H., Lee, H. K., Suh, H. J., & Chung, S. H. (1999). Journal of Microbiology and Biotechnology, 9, 223–226.

    CAS  Google Scholar 

  13. Powar, V. K., & Jagannathan, V. (1982). Journal of Bacteriology, 151, 1102–1108.

    CAS  Google Scholar 

  14. Shimizu, M. (1992). Bioscience, Biotechnology, and Biochemistry, 56, 266–1269.

    Google Scholar 

  15. Kerovuo, J., Lauraeus, M., Nurminen, P., Kalkkinen, N., & Apajalahti, J. (1998). Applied and Environmental Microbiology, 64, 2079–2085.

    CAS  Google Scholar 

  16. Choi, Y. M., Suh, H. J., & Kim, J. M. (2001). Journal of Protein Chemistry, 20, 287–292.

    Article  CAS  Google Scholar 

  17. Lei, X. G., & Stahl, C. H. (2000). Journal of Applied Animal Research, 17, 97–112.

    CAS  Google Scholar 

  18. Oh, B. C., Choi, W. C., Park, S., Kim, Y., & Oh, T. K. (2004). Applied Microbiology and Biotechnology, 63, 362–372.

    Article  CAS  Google Scholar 

  19. Tye, A. J., Siu, F. K., Leung, T. Y., & Lim, B. L. (2002). Applied Microbiology and Biotechnology, 59, 190–197.

    Article  CAS  Google Scholar 

  20. Ha, N. C., Oh, B. C., Shin, S., Kim, H. J., Oh, T. K., Kim, Y. O., et al. (2000). Nature Structural Biology, 7, 147–153.

    Article  CAS  Google Scholar 

  21. Elkhalil, E. A. I., Männer, K., Borriss, R., & Simon, O. (2007). British Poultry Science, 48, 64–70.

    Article  CAS  Google Scholar 

  22. Oh, B. C., Chang, B. S., Park, K. H., Ha, N. C., Kim, H. K., Oh, B. H., et al. (2001). Biochemistry, 40, 9669–9676.

    Article  CAS  Google Scholar 

  23. Kerovuo, J., Lappalainen, I., & Reinikainen, T. (2000). Biochemical and Biophysical Research Communications, 268, 365–369.

    Article  CAS  Google Scholar 

  24. Idriss, E. E., Makarewicz, O., Farouk, A., Rosner, K., Greiner, R., Bochow, H., et al. (2002). Microbiology, 148, 2097–2109.

    CAS  Google Scholar 

  25. Shin, S., Ha, N. C., Oh, B. C., Oh, T. K., & Oh, B. H. (2001). Structure, 9, 851–858.

    Article  CAS  Google Scholar 

  26. Kim, Y. O., Lee, J. K., Kim, H. K., Yu, J. H., & Oh, T. K. (1998). FEMS Microbiology Letters, 162, 185–191.

    Article  CAS  Google Scholar 

  27. van Etten, R. L., Davidson, R., Stevis, P. E., MacArthur, H., & Moore, D. L. (1991). Journal of Biological Chemistry, 266, 2313–2319.

    Google Scholar 

  28. Ullah, A. H. J., & Mullaney, E. J. (1996). Biochemical and Biophysical Research Communications, 227, 311–317.

    Article  CAS  Google Scholar 

  29. Song, G. Y., Wang, X. Y., & Wang, M. (2005). Protein Peptide Letters, 12, 533–535.

    Article  CAS  Google Scholar 

  30. Wang, X. Y., Meng, F. G., & Zhou, H. M. (2004). Biochemistry and Cell Biology, 82, 329–334.

    Article  CAS  Google Scholar 

  31. Ha, N. C., Kim, Y. O., Oh, T. K., & Oh, B. H. (1999). Acta Crystallographica. Section D, Biological Crytallography, 55, 691–693.

    Article  CAS  Google Scholar 

  32. Oh, B. C., Chang, B. S., Park, K. W., Ha, N. C., Kim, H. K., Oh, B. H., et al. (2006). Biochemistry, 40, 9669–9676.

    Article  CAS  Google Scholar 

  33. Greiner, R., Lim, B. L., Cheng, C., & Carlsson, N. G. (2007). Canadian Journal of Microbiology, 53, 488–495.

    Article  CAS  Google Scholar 

  34. Kerovuo, J., Rouvinen, J., & Hatzack, F. (2000). Biochemical Journal, 352, 623–628.

    Article  CAS  Google Scholar 

  35. Greiner, R., Farouk, A., Alminger, M. L., & Carlsson, N. G. (2002). Canadian Journal of Microbiology, 48, 986–994.

    Article  CAS  Google Scholar 

  36. Kim, Y. O., Lee, J. K., Oh, B. C., & Oh, T. K. (1999). Bioscience, Biotechnology, and Biochemistry, 63, 2205–2207.

    Article  CAS  Google Scholar 

  37. Brinch-Pedersen, H., Sorensen, L. D., & Holm, P. B. (2002). Trends in Plant Science, 7, 118–125.

    Article  CAS  Google Scholar 

  38. Yip, W., Wang, L., Cheng, C., Wu, W., Lung, S., & Lim, B. L. (2003). Biochemical and Biophysical Research Communications, 310, 1148–1154.

    Article  CAS  Google Scholar 

  39. Lung, S., Chan, W., Yip, W., Wang, L., Yeung, E. C., & Lim, B. L. (2005). Plant Science, 169, 341–349.

    Article  CAS  Google Scholar 

  40. Chan, W. L., Lung, S. C., & Lim, B. L. (2006). Protein Expression and Purification, 46, 100–106.

    Article  CAS  Google Scholar 

  41. Zeng, H., Yao, B., Zhou, W. H., & Fan, Z. Y. (2001). Journal of Aquaculture, 15, 87 (in Chinese).

    Google Scholar 

  42. Park, S. C., Choi, Y. W., & Oh, T. K. (1999). Journal of Veterinary Medical Science, 61, 1257–1259.

    Article  CAS  Google Scholar 

  43. Kaur, P., Kunze, G., & Satyanarayana, T. (2007). Critical Reviews in Biotechnology, 27, 93–109.

    Article  CAS  Google Scholar 

  44. Konietzny, U., & Greiner, R. (2004). Brazilian Journal of Microbiology, 35, 11–18.

    Article  CAS  Google Scholar 

  45. Konietzny, U., & Greiner, R. (2002). International Journal of Food Science & Technology, 37, 791–812.

    Article  CAS  Google Scholar 

  46. Igbasan, F. A., Manner, K., Miksch, G., Borriss, R., Farouk, A., & Simon, O. (2000). Archives of Animal Nutrition, 53, 353–373.

    Article  CAS  Google Scholar 

  47. Vats, P., & Banerjee, U. C. (2004). Enzyme and Microbial Technology, 35, 3–14.

    Article  CAS  Google Scholar 

Download references

Acknowledgments

The authors gratefully acknowledge Miss Shirley for the critical reading of the manuscript. This study was financially supported by the Science and Technology Department of Zhejiang Province of China (2006C12036).

Author information

Authors and Affiliations

  1. College of Animal Science, Zhejiang University, Hangzhou, 310029, People’s Republic China

    Shijun Fu, Jianyi Sun, Lichun Qian & Zhiyu Li

  2. The Key Laboratory of Molecular Animal Nutrition, Ministry of Education, Hangzhou, 310029, People’s Republic China

    Shijun Fu, Jianyi Sun & Zhiyu Li

Authors
  1. Shijun Fu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jianyi Sun
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Lichun Qian
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Zhiyu Li
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jianyi Sun.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fu, S., Sun, J., Qian, L. et al. Bacillus Phytases: Present Scenario and Future Perspectives. Appl Biochem Biotechnol 151, 1–8 (2008). https://doi.org/10.1007/s12010-008-8158-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s12010-008-8158-7

Keywords

Search

Navigation