Research and Technology in Neurocritical Care

Abstract

The daily practice of neurointensivists focuses on the recognition of subtle changes in the neurological examination, interactions between the brain and systemic derangements, and brain physiology. Common alterations such as fever, hyperglycemia, and hypotension have different consequences in patients with brain insults compared with patients of general medical illness. Various technologies have become available or are currently being developed. The session on “research and technology” of the first neurocritical care research conference held in Houston in September of 2009 was devoted to the discussion of the current status, and the research role of state-of-the art technologies in neurocritical patients including multi-modality neuromonitoring, biomarkers, neuroimaging, and “omics” research (proteomix, genomics, and metabolomics). We have summarized the topics discussed in this session. We have provided a brief overview of the current status of these technologies, and put forward recommendations for future research applications in the field of neurocritical care.

Appendix

The First Neurocritical Care Research Conference Investigators:

Organizing Committee

Chair: Suarez JI, MD, Baylor College of Medicine, Houston, TX; Calvillo E, RN, Baylor College of Medicine, Houston, TX; Geocadin R, MD, Johns Hopkins University, Baltimore, MD; Hall C, MD, UT Southwestern University; Le Roux PD, MD, University of Pennsylvania, Philadelphia, PA; Livesay S, MS, RN, ACNP, St Luke’s Episcopal Hospital, Houston, TX; Mayer SA, MD, Columbia University, New York, NY; Vespa P, MD, UCLA, Los Angeles, CA; Wijman CAC, MD, PhD, Stanford University, Palo Alto, CA; Zaidat OO, MD, MS, Medical College of Wisconsin, Milwaukee, WI.

Speakers

Bleck TP, RUSH School of Medicine, Chicago, IL; Chang C, MD, University of Hawaii, John A. Burns School of Medicine, Honolulu, HI; Cooper DJ, MD, Alfred Hospital and Monash University, Melbourne, Australia; Guntupalli KK, MD, Baylor College of Medicine, Houston, TX; Daily J, PhD, Case Western Reserve University, Cleveland, OH; Diringer MA, MD, Washington University School of Medicine, St Louis, MO; Robertson CS, MD, Baylor College of Medicine, Houston, TX; Hanley DF, MD, Johns Hopkins University, Baltimore, MD; Hemphill C III, MD, PhD, University of California in San Francisco, San Francisco, CA; Koroshetz W, MD, Deputy Director, NINDS, Bethesda. MD; Mirski MA, MD, PhD, Johns Hopkins University, Baltimore, MD; Palesch Y, PhD, Medical University of South Carolina; Qureshi AI, MD, University of Minnesota, Minneapolis, MN; Silbergleit R, MD, University of Michigan, Ann Arbor, MI; Smirnakis SM, MD, PhD, Baylor College of Medicine, Houston, TX; Szigeti K, MD, PhD, Baylor College of Medicine, Houston, TX.

Attendees

Adeoye O, MD, University of Cincinnati College of Medicine, Cincinnati, OH; Aisiku IP, University of Texas in Houston, Houston, TX; Bader MK, RN, Mission Viejo Hospital, Mission Viejo, CA; Ansari S, MD, Baylor College of Medicine, Houston, TX; Arshad ST, MD, Baylor College of Medicine, Houston, TX; Badjatia N, MD, Columbia University, New York, NY; Barazangi N, MD, Ph.D., Califorrnia Pacific Medical Center, San Francisco, CA; Bershad EM, MD, Baylor College of Medicine, Houston, TX; Boyd C, RN, MBA, St Luke’s Episcopal Hospital, Houston, TX; Claassen J, MD, Columbia University, New York, NY; Coplin W, MD, Wayne State University, Detroit, MI; Corry JJ, Henry Ford Hospital, Detroit, MI; Cruz-Florez S, MD, St Louis University, St Louis, MO; Dhar R, MD, Washington University School of Medicine, St Louis, MO; Dillon C, MS, Medical University of South Carolina, Charleston, SC; Divani AA, Ph.D., University of Minnesota, Minneapolis, MN; Duckworth E, MD, Baylor College of Medicine, Houston, TX; Ezzedine M, MD, University of Minnesota, Minneapolis, MN; Feen E, MD, St Louis University, St Louis, MO; Freeman W, MD, Mayo Clinic Florida, Jacksonville, FL; Frontera J, MD, Mount Sinai School of Medicine, New York, NY; Goodman JC, MD, Baylor College of Medicine, Houston, TX; Graffagnino C, MD, Duke University, Durham, NC; Hoesch RE, MD, PhD, Johns Hopkins University, Baltimore, MD; Ko NU, MD, University of California in San Francisco, San Francisco, CA; Koening M, MD, Johns Hopkins University, Baltimore, MD; Kramer A, University of Calgary, Calgary, AL, Canada; Lazaridis C, MD, Medical University of South Carolina, Charleston, SC; Lee JC, MD, Baylor College of Medicine, Houston, TX; Ling G, MD, PhD, US Armed Forces, Bethesda, MD; Macdonald RL, MD, Ph.D., University of Toronto, Toronto, ON, Canada; Malkoff M, MD, University of New Mexico, Albuquerque, NM; Mandava P, MD, Baylor College of Medicine, Houston, TX; Manno E, MD, Mayo Clinic, Rochester, MN; Martin H Renee, Ph.D., Medical University of South Carolina, Charleston, SC; Mawad M, MD, Baylor College of Medicine, Houston, TX; Mizrahi E, MD, Baylor College of Medicine, Houston, TX; McArthur DL, Ph.D., UCLA, Los Angeles, CA; Nathan B, MD, University of Virginia, Charlottesville, VA; Newmark M, MD, Baylor College of Medicine, Houston, TX; Nguyen T, PharmD, St Luke’s Episcopal Hospital, Houston, TX; Nyquist P, MD, Ph.D., The Johns Hopkins Hospital, Baltimore, MD; Oliveira J, Hospital San Rafael, Universidade Federale da Bahia, Salvador, Brazil; Olson DW, RN, PhD, Duke University, Durham, NC; Ougorets I, MD, New York Weil Medical College of Cornell University, New York, NY; Puppo C, MD, Universidad de la República, Montevideo, Uruguay; Pyne-Geithman G, Ph.D., University of Cincinnati, Cincinnati, OH; Rao CPV, Baylor College of Medicine, Houston, TX; Revuelto J, MD, Hospital Virgen del Rocio, Seville, Spain Rhoney D, PharmD, Detroit Receiving Hospital, Detroit, MI; Riviello J, MD, Baylor College of Medicine, Houston, TX; Sawaya R, MD, Baylor College of Medicine, Houston, TX; Seder D,MD, Maine Medical Center, Portland, ME; Sheth K, MD, Brigham and Women’s Hospital, Boston, MA; Souter M, MD, University of Washington, Seattle, WA; Strutt AM, Ph.D., Baylor College of Medicine, Houston, TX; Suri MFK, MD, University of Minnesota, Minneapolis, MN; Temes R, MD, RUSH Medical Center, Chicago, IL; Torbey MT, MD, MPH, Medical College of Wisconsin, Milwaukee, WI; Treggiari M, University of Washington, Seattle, WA; Urfy MZ, MD, Baylor College of Medicine, Houston, TX Varelas P, MD, Ph.D., Henry Ford Hospital, Detroit, MI; Wright W, MD, Emory University, Atlanta, GA; York MK, Ph.D., Baylor College of Medicine, Houston, TX; Ziai W, MD, Johns Hopkins University, Baltimore, MD; Zwillman M, MD, The Methodist Hospital, Houston, TX.