Abstract
Recurrent abdominal pain is a common problem in children that may need invasive procedures for diagnosis. Hereditary angioedema (HAE) is rarely considered in the differential diagnosis. Here it is reported a girl with HAE, who presented initially as recurrent abdominal pain without cutaneous manifestations. Each episode was managed elsewhere as an acute surgical emergency and an exploratory laparotomy was planned. Diagnosis was confirmed by quantitative assay of C1 inhibitor. On detailed evaluation, many members of her family were affected.
Similar content being viewed by others
References
Avnish KS, Velu N, Jasjith S, Ved PD. Hereditary angioedema with recurrent abdominal pain. Indian Gastroenterol 2002; 21: 82–83.
Weinstock LB, Kothari T, Sharma SN. Recurrent abdominal pain as the sole manifestation of hereditary angioedema in multiple family members. Gastroenterology 1987; 93: 1116–1118.
Arun KB, Surjit Singh, Latha Kumar. Hereditary Angioedema. Indian Pediatrics 1999; 36: 187–189.
Gompels MM, Lock RJ, Abinun M et al. C1 inhibitor deficiency: consensus document. Clinical and experimental Immunology 2005; 139: 379–394.
Bork K, Barnstedt SE. Treatment of 193 episodes of laryngeal edema with C1 inhibitor concentrate in patients with HAE. Arch Intern Med 2001; 161: 714–718.
Gelfand JA, Sherins RJ, Alling DW et al. Treatment of hereditary angioedema with danazol: reversal of clinical and biochemical abnormalities. N Engl J Med 1976; 295: 1444.
Waytes AT, Rosen FS, Frank MM. Treatment of hereditary angioedema with a vapor treated C1 inhibitor concentrate. N Engl J Med 1996; 334: 1630–1634.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Janardhanan, D., Nair, S. & Subramanian, T.S. Recurrent abdominal pain due to hereditary angioedema. Indian J Pediatr 74, 83–84 (2007). https://doi.org/10.1007/s12098-007-0034-x
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-007-0034-x