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Seroepidemiology of Hepatitis B in Greek Children 6 Years After the Implementation of Universal Vaccination

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Abstract

The seroepidemiology of hepatitis B in children living in Greece 6 years post-implementation of universal infant immunization (1998) was studied. We collected 90–100 sera/year of age, stratified by geographic region. The prevalence of HbsAg(+) was 0.6% (95% CI 0.3–1.3) whereas 4.5% (95% CI 3.4–5.9%) of children over 12 months of age had evidence of past HBV infection. A significant decline in the prevalence of past infection between children born before and after 1998 (5.5% vs 2.9%; RR = 1.9, 95% CI 1.03–3.5) was noted. Conversely, the prevalence of past HBV infection did not change significantly among immigrant children. Reinforcement of early vaccination of immigrant population is necessary.

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Correspondence to V. Papaevangelou.

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Papaevangelou, V., Hadjichristodoulou, C., Cassimos, D.C. et al. Seroepidemiology of Hepatitis B in Greek Children 6 Years After the Implementation of Universal Vaccination. Infection 36, 135–139 (2008). https://doi.org/10.1007/s15010-007-7096-6

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  • DOI: https://doi.org/10.1007/s15010-007-7096-6

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