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Neural Crest Inducing Signals

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Neural Crest Induction and Differentiation

Part of the book series: Advances in Experimental Medicine and Biology ((volume 589))

Abstract

The formation of the neural crest has been traditionally considered a classic example of secondary induction, where signals form one tissue elicit a response in a competent responding tissue. Interactions of the neural plate with paraxial mesoderm or nonneural ectoderm can generate neural crest. Several signaling pathways converge at the border between neural and nonneural ectoderm where the neural crest will form. Among the molecules identified in this process are members of the BMP, Wnt, FGF and Notch signaling pathways. The concerted action of these nals and their downstream targets will define the identity of the neural crest.

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Author information

Authors and Affiliations

  1. House Ear Institute, Los Angeles, California, USA

    Martín L. Basch

  2. 139-74 Beckman Institute, California Institute of Technology, Pasadena, California, 91125, USA

    Marianne Bronner-Fraser

Authors
  1. Martín L. Basch
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  2. Marianne Bronner-Fraser
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Editor information

Editors and Affiliations

  1. Department of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

    Jean-Pierre Saint-Jeannet Ph.D.

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© 2006 Landes Bioscience and Springer Science+Business Media

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Basch, M.L., Bronner-Fraser, M. (2006). Neural Crest Inducing Signals. In: Saint-Jeannet, JP. (eds) Neural Crest Induction and Differentiation. Advances in Experimental Medicine and Biology, vol 589. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-46954-6_2

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