Abstract
It is estimated that approximately 63,000 chemicals are in common use and that significant quantities of several hundred new chemicals are added to the environment every year.p(1) A number of chemicals have been shown to be carcinogenic for humans. It is essential, therefore, that those presenting a risk be readily identified so they can be either removed from the environment or at least regulated to minimize further exposure. Traditionally, chemicals are evaluated for their carcinogenic potential in conventional animal test systems that are costly and time-consuming. Because of such limitations, only a few hundred chemicals can be tested yearly.
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Pienta, R.J. (1980). Transformation of Syrian Hamster Embryo Cells by Diverse Chemicals and Correlation with Their Reported Carcinogenic and Mutagenic Activities. In: de Serres, F.J., Hollaender, A. (eds) Chemical Mutagens. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-3072-1_7
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