Abstract
Exposure of male mice to trichloroethylene vapours during 24 h at levels of 50,202 and 450 ppm did not reveal mutagenic effects in the dominant lethal assay. The following parameters were registered and evaluated: Fertilization rate, post-implantation loss, preemplantation loss and dominant lethal mutations.
Zusammenfassung
Die Belastung von männlichen Mäusen mit TrichloräthylenDämpfen in Konzentrationen von 50, 202 und 450 ppm über 24 h zeigte keine mutagenen Wirkungen im Dominant-Letal-Test. Folgende Parameter wurden registriert und bewertet: Befruchtungsrate, postimplantativer Verlust, präimplantativer Verlust und dominante letale Mutationen.
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Slacik-Erben, R., Roll, R., Franke, G. et al. Trichloroethylene vapours do not produce dominant lethal mutations in male mice. Arch. Toxicol. 45, 37–44 (1980). https://doi.org/10.1007/BF00303293
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DOI: https://doi.org/10.1007/BF00303293