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Investigations on the influence of immunodepressive means on the chemical carcinogenesis in rats

Untersuchungen an Ratten zur Beeinflussung der chemischen Carcinogenese durch immunodepressive Maßnahmen

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Summary

The carcinogenicity of cyclophosphamide in rats could not be influenced by additional immunodepressive treatment with hydrocortisone. In the same way the carcinogenic effect of 3,4-benzopyrene could not be promoted by the immunodepressants cyclophosphamide and hydrocortisone.

Zusammenfassung

Die carcinogene Wirkung von Cyclophosphamid bei Ratten konnte durch zusätzliche immunodepressiv wirkende Behandlungen mit Hydrocortison nicht verstärkt werden. Ebenso ließ sich die carcinogene Wirkung von 3,4-Benzpyren durch Immunodepression mittels Cyclophosphamid oder Hydrocortison nicht im fördernden Sinne beeinflussen.

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Dedicated to Professor Hermann Druckrey on the occasion of his 70th birthday, July 27th, 1974.

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Schmähl, D. Investigations on the influence of immunodepressive means on the chemical carcinogenesis in rats. Z. Krebsforsch. 81, 211–215 (1974). https://doi.org/10.1007/BF00305020

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  • DOI: https://doi.org/10.1007/BF00305020

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