Biochimica et Biophysica Acta (BBA) - Bioenergetics
ColloquiaThe role of futile cycles in the energetics of bacterial growth
References (22)
- et al.
J. Biol. Chem.
(1980) FEMS Microbiol. Lett.
(1977)- et al.
FEMS Microbiol. Lett.
(1983) - et al.
FEMS Microbiol. Lett.
(1984) - et al.
Biochim. Biophys. Acta
(1986) FEBS Lett.
(1985)FEMS Microbiol. Rev.
(1985)- et al.
Biochim. Biophys. Acta
(1977) FEMS Microbiol. Lett.
(1983)- et al.
Biochem. J.
(1972)
J. Bacteriol.
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Microbial Metabolism Modulates Antibiotic Susceptibility within the Murine Gut Microbiome
2019, Cell MetabolismCitation Excerpt :Three major classes of bactericidal drugs—beta-lactams, aminoglycosides, and fluoroquinolones—have been shown to increase the abundance of reactive oxygen species (ROS), nicotinamide adenine dinucleotide (NAD)+, and tricarboxylic acid (TCA) cycle intermediates, suggesting a temporary induction of metabolic activity (Belenky et al., 2015; Dwyer et al., 2014; Ferrándiz et al., 2015; Hoeksema et al., 2018; Lobritz et al., 2015; Yang et al., 2018). This increase in metabolic activity is likely caused in part by the induction of deleterious futile cycles that elevate ATP consumption (Adolfsen and Brynildsen, 2015; Belenky et al., 2015; Cho et al., 2014; Lobritz et al., 2015; Neijssel et al., 1990). Furthermore, artificially elevating respiratory metabolism via genetic disruptions or supplementation with TCA cycle metabolites can promote susceptibility to bactericidal drugs (Lobritz et al., 2015; Meylan et al., 2017, 2018; Su et al., 2018).
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